J. A. Jones

Analysis of uveal melanoma scRNA sequencing data identifies neoplastic-immune hybrid cells that exhibit metastatic potential

The paper identifies neoplastic-immune hybrid cells in uveal melanoma scRNA-seq data that exhibit metastatic potential through gene expression and ligand-receptor analysis.

Assessing the relationship between female aggression and male phenotype in two sister Malurus fairywren species

The paper compares female aggression and male phenotype in two fairywren species, finding interspecific differences but no intraspecific correlation between male quality and female aggression.

Pharmacological and behavioral effects of tryptamines present in psilocybin-containing mushrooms

This study compares the pharmacological and behavioral effects of tryptamines in psilocybin-containing mushrooms, finding that norbaeocystin may have therapeutic potential similar to psilocybin without causing hallucinations.

Structural basis for peroxidase encapsulation in a protein nanocompartment

This study determines the structural basis for encapsulating dye-decolorizing peroxidases in a protein nanocompartment using cryo-EM and mutagenesis.

Role of Adenosine Deaminase in Prostate Cancer Progression

This study identifies adenosine deaminase (ADA) as a driver of prostate cancer progression and metastasis through metabolomics and in vitro/in vivo experiments.

Vascular Smooth Muscle Cell Mechanotransduction Through Serum and Glucocorticoid Inducible Kinase-1 Promotes Interleukin-6 Production and Macrophage Accumulation in Murine Hypertension

This study shows that SGK-1 in vascular smooth muscle cells promotes IL-6 and macrophage accumulation in hypertension via mechanotransduction and AngII signaling.

Exploring the Extreme Acid Tolerance of a Dynamic Protein Nanocage

This study characterizes AaEnc, an acid-stable encapsulin nanocage from Acidipropionibacterium acidipropionici, revealing its pH-dependent dynamic pore and extreme acid tolerance.

Human Cardiac Organoids to Model COVID-19 Cytokine Storm Induced Cardiac Injuries

This study uses human cardiac organoids to model COVID-19-induced cardiac injuries by simulating cytokine storm effects and evaluates potential therapeutic interventions.

Lipid Alterations in African American Prostate Cancer

The paper identifies lipid alterations associated with prostate cancer disparities in African American men through lipidomics profiling of tumor and benign tissues.

Male White-shouldered Fairywrens (Malurus alboscapulatus) elevate testosterone when courting females but not during territorial challenges

The paper tests two versions of the challenge hypothesis in White-shouldered Fairywrens, finding testosterone elevation during courtship but not territorial challenges.

Testosterone induces a female ornament followed by enhanced territoriality in a tropical songbird

Testosterone induces partial ornamentation in unornamented female birds, which is followed by increased territorial behavior, suggesting ornamentation drives aggression rather than testosterone alone.

Glucose signaling is important for nutrient adaptation during differentiation of pleomorphic African trypanosomes

This study shows glucose depletion triggers differentiation in African trypanosomes, with glucose acting as both a metabolic substrate and signaling molecule.