Diet induced obesity and type 2 diabetes drives exacerbated sex-associated disease profiles in K18-hACE2-mice challenged with SARS-CoV-2
K. Lee, B. Russ, T. Wong, A. M. Horspool, M. T. Winters, M. Barbier, J. R. Bevere, I. Martinez, F. H. Damron, H. A. Cyphert
This study shows that diet-induced obesity and type 2 diabetes in female mice worsen SARS-CoV-2 disease outcomes compared to males and normal diet mice.
bioRxiv · Apr 26, 2022 · PreprintImmunology