Author
M. Barbier
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
Click to filter author papersSignature Assays, Organisms & Methods
Click to filter · or open tagActivity by Year
2018-2024 · peak 7/yrCo-Author Collaboration Network
10 top collaborators · 20 mutual co-author links30 papers
Recent·Most cited
Collective dynamical regimes predict invasion success and impacts in microbial communities
J. Hu, M. Barbier, G. Bunin, J. Gore
The paper shows that invasion success and impacts in microbial communities depend on dynamics, interaction strength, and diversity, with more fluctuating and diverse communities being more invasible and having larger ecological effects.
bioRxiv · Feb 5, 2024Ecology
A taxonomy of multiple stable states in complex ecological communities
G. Aguade-Gorgorio, J.-F. Arnoldi, M. Barbier, S. Kefi
The paper investigates multiple stable states in complex systems, identifying four regimes of multistability and their fingerprints, which can be used to analyze regime shifts in ecological communities.
bioRxiv · Aug 30, 2023Ecology
Getting More by Asking for Less: Linking Species Interactions to Species Co-Distributions in Metacommunities
M. Barbier, G. Bunin, M. A. Leibold
This paper shows that inferring precise species interactions from spatial distribution patterns is challenging, but estimating statistical moments of interaction distributions is more robust.
bioRxiv · Jun 4, 2023Ecology
Intranasal VLP-RBD vaccine adjuvanted with BECC470 confers immunity against Delta SARS-CoV-2 challenge in K18-hACE2-mice
F. H. Damron, K. S. Lee, N. A. Rader, O. A. Miller-Stump, M. Cooper, T. Y. Wong, M. S. Amin, M. Barbier, J. R. Bevere, R. K. Ernst
This study shows an intranasal VLP-RBD vaccine with BECC470 adjuvant provides protection against Delta SARS-CoV-2 in mice, with mucosal immunity and reduced lung inflammation.
bioRxiv · Apr 25, 2023Immunology
Addition of adjuvant to DTaP modulates vaccine-induced immunological responses but is insufficient to improve protection in CD-1 mice
K. L. Weaver, G. M. Pyles, S. R. Dublin, A. B. Huckaby, S. J. Miller, M. d. l. P. Gutierrez, E. Sen-Kilic, W. T. Witt, D. T. Boehm, F. H. Damron, M. Barbier
This study evaluates if adding adjuvants to DTaP improves protection in CD-1 mice against Bordetella pertussis, finding that while adjuvants enhance immune markers, they do not improve protection.
bioRxiv · Mar 3, 2023 · PreprintImmunology
The heme-responsive PrrH sRNA regulates Pseudomonas aeruginosa pyochelin gene expression
T.-M. Hoang, W. Huang, J. Gans, E. S. Nowak, M. Barbier, A. Wilks, M. A. Kane, A. G. Oglesby
This study identifies pyochelin biosynthesis genes as a target of the heme-responsive PrrH sRNA and shows environmental factors like light affect PrrH function.
bioRxiv · Jan 19, 2023 · PreprintMicrobiology
How collectively integrated are ecological communities?
Y. Zelnik, N. Galiana, M. Barbier, M. Loreau, E. Galbraith, J.-F. Arnoldi
The paper investigates whether ecological community dynamics depend more on direct species interactions or indirect feedbacks, showing that the spectral radius of the interaction matrix determines the contribution of indirect pathways.
bioRxiv · Dec 29, 2022Ecology
Molecular engineering of a cryptic epitope in Spike RBD improves manufacturability and neutralizing breadth against SARS-CoV-2 variants
S. A. Rodriguez-Aponte, N. C. Dalvie, T. Y. Wong, R. S. Johnston, C. A. Naranjo, S. Bajoria, O. S. Kumru, K. Kaur, B. P. Russ, K. S. Lee, H. A. Cyphert, M. Barbier, H. D. Rao, M. P. Rajurkar, R. R. Lothe, , J. C. Love
bioRxiv · Sep 14, 2022Bioengineering
Diet induced obesity and type 2 diabetes drives exacerbated sex-associated disease profiles in K18-hACE2-mice challenged with SARS-CoV-2
K. Lee, B. Russ, T. Wong, A. M. Horspool, M. T. Winters, M. Barbier, J. R. Bevere, I. Martinez, F. H. Damron, H. A. Cyphert
This study shows that diet-induced obesity and type 2 diabetes in female mice worsen SARS-CoV-2 disease outcomes compared to males and normal diet mice.
bioRxiv · Apr 26, 2022 · PreprintImmunology
SARS-CoV-2 Delta variant induces enhanced pathology and inflammatory responses in K18-hACE2 mice
K. S. Lee, T. Y. Wong, B. P. Russ, A. M. Horspool, O. Miller, N. Rader, J. P. Givi, M. T. Winters, Z. Y. Wong, H. A. Cyphert, J. Denvir, P. G. Stoilov, M. Barbier, N. Roan, M. S. Amin, , F. H. Damron
This study compares the pathogenesis of SARS-CoV-2 Delta and Alpha variants in K18-hACE2 mice, finding Delta causes more inflammation, tissue damage, and interferon responses.
bioRxiv · Jan 18, 2022Immunology
Emergent phases of ecological diversity and dynamics mapped in microcosms
J. Hu, D. R. Amor, M. Barbier, G. Bunin, J. Gore
The paper demonstrates predictable emergent diversity and dynamics in microbial ecosystems by showing transitions between distinct dynamical phases as species number or interaction strength increases.
bioRxiv · Oct 28, 2021Biophysics
Linking intrinsic scales of ecological processes to characteristic scales of biodiversity and functioning patterns
Y. R. Zelnik, M. Barbier, D. W. Shanafelt, M. Loreau, R. M. Germain
This study uses simulations to explore how different ecological process scales affect biodiversity and ecosystem functioning patterns, finding that dispersal and species interactions have opposing effects on spatial heterogeneity.
bioRxiv · Oct 11, 2021Ecology
Long-term analysis of pertussis vaccine immunity uncovers a memory B cell response to whole cell pertussis immunization that is absent from acellular immunized mice
K. L. Weaver, C. B. Blackwood, A. M. Horspool, G. M. Pyles, E. Sen-Kilic, E. M. Grayson, A. B. Huckaby, W. T. Witt, M. A. DeJong, M. A. Wolf, F. H. Damron, M. Barbier
This study compares long-term immune responses to whole cell and acellular pertussis vaccines in mice, finding unique memory B cell responses in wP-vaccinated mice.
bioRxiv · Oct 1, 2021 · PreprintImmunology
Mucosal immunization with DTaP confers protection against Bordetella pertussis infection and cough in Sprague-Dawley rats
J. M. Hall, G. J. Bitzer, M. A. DeJong, J. Kang, T. Y. Wong, M. A. Wolf, J. R. Bevere, M. Barbier, F. H. Damron
This study shows that mucosal vaccination with aP protects against Bp infection and cough in rats, inducing mucosal immunity and reducing bacterial burden.
bioRxiv · Jun 21, 2021Microbiology
Re-investigating the coughing rat model of pertussis to understand Bordetella pertussis pathogenesis
J. Hall, J. Kang, S. M. Kenney, T. Y. Wong, G. J. Bitzer, C. O. Kelly, C. A. Kisamore, D. Boehm, M. A. DeJong, M. A. Wolf, E. Sen-Kilic, A. M. Horspool, J. R. Bevere, M. Barbier, F. H. Damron
This study uses a rat model to compare disease manifestations between two genetically distinct Bordetella pertussis strains, finding that D420 induces more severe coughing and immune responses than Tohama 1.
bioRxiv · Apr 2, 2021Immunology
Burkholderia collagen-like protein 8, Bucl8, is a unique outer membrane component of a tetrapartite efflux pump in Burkholderia pseudomallei and Burkholderia mallei
M. E. Grund, S. J. Choi, D. H. McNitt, M. Barbier, G. Hu, P. R. LaSala, C. K. Cote, R. Berisio, S. Lukomski
This study identifies Bucl8 as a unique outer membrane component of a tetrapartite efflux pump in Burkholderia pseudomallei and Burkholderia mallei, showing its role in fusaric acid resistance, fibrinogen binding, and growth.
bioRxiv · Sep 18, 2020Microbiology
Fitness and community feedbacks: the two axes that drive long-term invasion impacts
J.-F. Arnoldi, M. Barbier, R. Kelly, G. Barabas, A. L. Jackson
The paper develops an analytical method to predict long-term community impacts of invasions by considering fitness and feedback mechanisms across different ecological models.
bioRxiv · Apr 18, 2020 · PreprintEcology
Can biomass distribution across trophic levels predict trophic cascades?
N. Galiana, J.-F. Arnoldi, M. Barbier, A. Acloque, C. de Manzancourt, M. Loreau
This study shows that biomass distribution and trophic cascades are linked through trophic dissipation, using data from aquatic mesocosm experiments.
bioRxiv · Apr 4, 2020Ecology
Fingerprints of high-dimensional coexistence in complex ecosystems
M. Barbier, C. de Mazancourt, M. Loreau, G. Bunin
This study explores high-dimensional coexistence in ecosystems using grassland biodiversity data, showing that biodiversity arises from collective organization rather than individual species interactions.
bioRxiv · Mar 10, 2020Ecology
Ecotone formation through ecological niche construction: the role of biodiversity and species interactions
K. Liautaud, M. Barbier, M. Loreau
This study shows that biodiversity and species interactions, particularly through ecological niche construction, can lead to the formation of ecotones through indirect environmental modifications.
bioRxiv · Jan 12, 2020Ecology
Elevated levels of interleukin-27 in early life compromise protective immunity during neonatal sepsis
B. G. Seman, J. K. Vance, T. W. Rawson, M. R. Witt, A. B. Huckaby, J. M. Povroznik, S. D. Bradford, M. Barbier, C. M. Robinson
This study shows elevated IL-27 in neonates worsens sepsis outcomes by impairing bacterial control and promoting inflammation.
bioRxiv · Sep 20, 2019Immunology
Can endogenous fluctuations persist in high-diversity ecosystems?
F. Roy, M. Barbier, G. Biroli, G. Bunin
The paper shows high-diversity spatial ecosystems can exhibit persistent non-equilibrium states with chaotic dynamics, driven by endogenous fluctuations rather than external perturbations.
bioRxiv · Aug 9, 2019 · PreprintEcology
Distribution and abundance of bottlenose dolphin (Tursiops truncatus) over the French Mediterranean continental shelf
H. Labach, C. Azzinari, M. Barbier, C. Cesarini, B. Daniel, L. David, F. Dhermain, N. Di-Meglio, B. Guichard, J. Jourdan, N. Robert, M. Roul, N. Tomasi, O. Gimenez
The paper estimates the size of the bottlenose dolphin population in French Mediterranean waters using photo-identification and capture-recapture methods, finding 557 individuals.
bioRxiv · Aug 2, 2019 · PreprintEcology
Characterizing the innate and adaptive responses of immunized mice to Bordetella pertussis infection using in vivo imaging and transcriptomic analysis
D. T. Boehm, M. E. Varney, T. Y. Wong, E. S. Nowak, E. Sen-Kilic, J. M. Hall, S. D. Bradford, K. A. Begley, J. U. Bevere, M. S. Epperly, J. A. Maynard, E. L. Hewlett, M. Barbier, F. H. Damron
This study uses in vivo imaging and transcriptomic analysis to compare immune responses in mice vaccinated against B. pertussis, finding differential gene expression and neutrophil dynamics across vaccine types.
bioRxiv · Jun 18, 2019 · PreprintImmunology
Compensatory evolution drives multidrug-resistant tuberculosis in Central Asia
M. Merker, M. Barbier, H. Cox, J.-P. Rasigade, S. Feuerriegel, T. A. Kohl, R. Diel, S. Borrell, S. Gagneux, V. Nikolayevskyy, S. Andres, U. Nübel, P. Supply, T. Wirth, S. Niemann
The paper investigates the evolutionary mechanisms behind multidrug-resistant tuberculosis in Central Asia, finding that compensatory mutations enhance resistance and transmission success.
bioRxiv · May 31, 2018Evolutionary Biology
Generic assembly patterns in complex ecological communities
M. Barbier, J.-F. Arnoldi, G. Bunin, M. Loreau
The paper shows that generic behaviors in ecological communities can be predicted using a random model, highlighting the role of statistical properties over detailed structure.
bioRxiv · Jan 21, 2018Ecology