I. Martinez

Curcumin and 5-bromoindole-3-carboxaldehyde inhibit the production of Quorum sensing-dependent virulence factors in Pseudomonas aeruginosa

This study evaluates curcumin and 5-bromoindole-3-carboxaldehyde for inhibiting quorum sensing-dependent virulence factors in Pseudomonas aeruginosa strains.

Transposition, duplication, and divergence of the telomerase RNA underlies the Mimulus telomere evolution

The paper identifies transposition, duplication, and divergence of the telomerase RNA as the mechanism driving telomere sequence evolution in Mimulus species.

Historical use of coastal wetlands by small-scale fisheries in the Northern Gulf of California

The paper uses local ecological knowledge to analyze historical changes in coastal wetland fisheries in the Northern Gulf of California, finding declining species abundance and shifting baselines.

Diet induced obesity and type 2 diabetes drives exacerbated sex-associated disease profiles in K18-hACE2-mice challenged with SARS-CoV-2

This study shows that diet-induced obesity and type 2 diabetes in female mice worsen SARS-CoV-2 disease outcomes compared to males and normal diet mice.

SARS-CoV-2 Delta variant induces enhanced pathology and inflammatory responses in K18-hACE2 mice

This study compares the pathogenesis of SARS-CoV-2 Delta and Alpha variants in K18-hACE2 mice, finding Delta causes more inflammation, tissue damage, and interferon responses.

Prenatal cadmium exposure alters proliferation in mouse CD4+ T cells via LncRNA Snhg7

This study shows prenatal cadmium exposure increases lncSnhg7 and GALNT7 in mouse CD4+ T cells, enhancing proliferation through miR-34a regulation.

SARS-CoV-2 B.1.1.7 and B.1.351 variants of concern induce lethal disease in K18-hACE2 transgenic mice despite convalescent plasma therapy

This study compares the pathogenicity and immune response of SARS-CoV-2 variants B.1.1.7 and B.1.351 with WA-1 in mice, showing reduced protection from convalescent plasma against the variants.

Depsipeptide nucleic acids: prebiotic formation, oligomerization, and self-assembly of a new candidate proto-nucleic acid

This study introduces depsipeptide nucleic acid as a prebiotic candidate for the first informational polymer, showing its spontaneous formation and self-assembly under plausible early Earth conditions.