Author

H. A. Cyphert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

F. H. Damron· 4 shared J. R. Bevere· 4 shared A. M. Horspool· 3 shared B. P. Russ· 3 shared I. Martinez· 3 shared K. S. Lee· 3 shared M. Barbier· 3 shared M. T. Winters· 3 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

F. H. Damron

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Molecular engineering of a cryptic epitope in Spike RBD improves manufacturability and neutralizing breadth against SARS-CoV-2 variants

S. A. Rodriguez-Aponte, N. C. Dalvie, T. Y. Wong, R. S. Johnston, C. A. Naranjo, S. Bajoria, O. S. Kumru, K. Kaur, B. P. Russ, K. S. Lee, H. A. Cyphert, M. Barbier, H. D. Rao, M. P. Rajurkar, R. R. Lothe, , J. C. Love

bioRxiv · Sep 14, 2022Bioengineering

Diet induced obesity and type 2 diabetes drives exacerbated sex-associated disease profiles in K18-hACE2-mice challenged with SARS-CoV-2

K. Lee, B. Russ, T. Wong, A. M. Horspool, M. T. Winters, M. Barbier, J. R. Bevere, I. Martinez, F. H. Damron, H. A. Cyphert

This study shows that diet-induced obesity and type 2 diabetes in female mice worsen SARS-CoV-2 disease outcomes compared to males and normal diet mice.

bioRxiv · Apr 26, 2022 · PreprintImmunology

SARS-CoV-2 Delta variant induces enhanced pathology and inflammatory responses in K18-hACE2 mice

K. S. Lee, T. Y. Wong, B. P. Russ, A. M. Horspool, O. Miller, N. Rader, J. P. Givi, M. T. Winters, Z. Y. Wong, H. A. Cyphert, J. Denvir, P. G. Stoilov, M. Barbier, N. Roan, M. S. Amin, , F. H. Damron

This study compares the pathogenesis of SARS-CoV-2 Delta and Alpha variants in K18-hACE2 mice, finding Delta causes more inflammation, tissue damage, and interferon responses.

bioRxiv · Jan 18, 2022Immunology

SARS-CoV-2 B.1.1.7 and B.1.351 variants of concern induce lethal disease in K18-hACE2 transgenic mice despite convalescent plasma therapy

A. M. Horspool, C. Ye, T. Y. Wong, B. P. Russ, K. S. Lee, M. T. Winters, J. R. Bevere, T. Kieffer, I. Martinez, J. Sourimant, A. L. Greninger, R. K. Plemper, J. Denvir, H. A. Cyphert, J. B. Torrelles, , F. H. Damron

This study compares the pathogenicity and immune response of SARS-CoV-2 variants B.1.1.7 and B.1.351 with WA-1 in mice, showing reduced protection from convalescent plasma against the variants.

bioRxiv · May 5, 2021 · PreprintMicrobiology