F. H. Damron

Comparison of gastric inflammation and metaplasia induced by Helicobacter pylori or Helicobacter felis colonization in mice

This study compares gastric inflammation and metaplasia induced by Helicobacter pylori or Helicobacter felis in mice, finding that HF causes more severe inflammation and atrophy than HP.

Post-acute immunological and behavioral sequelae in mice after Omicron infection

This study investigates post-acute immunological and behavioral effects in mice after Omicron infection, showing vaccination reduces pulmonary immune perturbations and behavioral deficits.

Intranasal VLP-RBD vaccine adjuvanted with BECC470 confers immunity against Delta SARS-CoV-2 challenge in K18-hACE2-mice

This study shows an intranasal VLP-RBD vaccine with BECC470 adjuvant provides protection against Delta SARS-CoV-2 in mice, with mucosal immunity and reduced lung inflammation.

Addition of adjuvant to DTaP modulates vaccine-induced immunological responses but is insufficient to improve protection in CD-1 mice

This study evaluates if adding adjuvants to DTaP improves protection in CD-1 mice against Bordetella pertussis, finding that while adjuvants enhance immune markers, they do not improve protection.

Molecular engineering of a cryptic epitope in Spike RBD improves manufacturability and neutralizing breadth against SARS-CoV-2 variants

Diet induced obesity and type 2 diabetes drives exacerbated sex-associated disease profiles in K18-hACE2-mice challenged with SARS-CoV-2

This study shows that diet-induced obesity and type 2 diabetes in female mice worsen SARS-CoV-2 disease outcomes compared to males and normal diet mice.

SARS-CoV-2 Delta variant induces enhanced pathology and inflammatory responses in K18-hACE2 mice

This study compares the pathogenesis of SARS-CoV-2 Delta and Alpha variants in K18-hACE2 mice, finding Delta causes more inflammation, tissue damage, and interferon responses.

Long-term analysis of pertussis vaccine immunity uncovers a memory B cell response to whole cell pertussis immunization that is absent from acellular immunized mice

This study compares long-term immune responses to whole cell and acellular pertussis vaccines in mice, finding unique memory B cell responses in wP-vaccinated mice.

Mucosal immunization with DTaP confers protection against Bordetella pertussis infection and cough in Sprague-Dawley rats

This study shows that mucosal vaccination with aP protects against Bp infection and cough in rats, inducing mucosal immunity and reducing bacterial burden.

SARS-CoV-2 B.1.1.7 and B.1.351 variants of concern induce lethal disease in K18-hACE2 transgenic mice despite convalescent plasma therapy

This study compares the pathogenicity and immune response of SARS-CoV-2 variants B.1.1.7 and B.1.351 with WA-1 in mice, showing reduced protection from convalescent plasma against the variants.

Re-investigating the coughing rat model of pertussis to understand Bordetella pertussis pathogenesis

This study uses a rat model to compare disease manifestations between two genetically distinct Bordetella pertussis strains, finding that D420 induces more severe coughing and immune responses than Tohama 1.

Characterizing the innate and adaptive responses of immunized mice to Bordetella pertussis infection using in vivo imaging and transcriptomic analysis

This study uses in vivo imaging and transcriptomic analysis to compare immune responses in mice vaccinated against B. pertussis, finding differential gene expression and neutrophil dynamics across vaccine types.