Author

B. S. Saller

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

O. Gross· 2 shared A. Boettcher· 1 shared A. Kostina· 1 shared C. Agarinis· 1 shared C. J. Farady· 1 shared C. J. Gross· 1 shared C. K. Go· 1 shared C. Parker· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

O. Gross

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2 papers

Recent·Most cited

Sequentially activated death complexes regulate pyroptosis and IL-1β release in response to Yersinia blockade of immune signaling

R. S. Wertman, C. K. Go, B. S. Saller, O. Gross, P. Scott, I. E. Brodsky

This study shows that Yersinia-induced cell death and IL-1β release are driven by spatially and temporally distinct but functionally connected death complexes.

bioRxiv · Sep 14, 2023 · PreprintImmunology

Tyrosine kinase inhibitors trigger lysosomal damage-associated cell lysis to activate the NLRP3 inflammasome

E. Neuwirt, G. Magnani, T. Cikovic, A. Kostina, S. Wohrle, S. Flemming, N. J. Fischenich, B. S. Saller, O. Gorka, S. Renner, C. Agarinis, C. Parker, A. Boettcher, C. J. Farady, R. Backofen, , O. Gross

A small molecule screen identifies tyrosine kinase inhibitors that cause lysosomal damage, leading to cell lysis and NLRP3 inflammasome activation via K+ efflux.

bioRxiv · Feb 19, 2022 · PreprintImmunology