Author

R. P. Bohm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 6 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:host-pathogen & immune response· 6 Organism:non-human primate· 6 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:cell-cell communication· 2 Organism:Arabidopsis· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

J. Rappaport· 6 shared N. J. Maness· 6 shared K. Russell-Lodrigue· 5 shared N. Golden· 5 shared P. P. Aye· 5 shared R. V. Blair· 5 shared C. J. Roy· 4 shared L. A. Doyle-Meyers· 4 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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6 shared papersImmunology

J. Rappaport

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

The Impact of SIV-Induced Immunodeficiency on Clinical Manifestation, Immune Response, and Viral Dynamics in SARS-CoV-2 Coinfection

A. Melton, L. A. Rowe, T. Penney, C. Krzykwa, K. Goff, S. E. Scheuermann, H. J. Melton, K. Williams, N. Golden, K. Moore Green, B. Smith, K. Russell-Lodrigue, J. P. Dufour, L. A. Doyle-Meyers, F. Schiro, , N. J. Maness

This study examines how SIV-induced immunodeficiency affects SARS-CoV-2 infection in macaques, finding that while immune responses are impaired, viral kinetics and evolution remain unchanged.

bioRxiv · Nov 15, 2023 · PreprintImmunology

Durable protection against SARS-CoV-2 Omicron induced by an adjuvanted subunit vaccine

P. S. Arunachalam, Y. Feng, U. Ashraf, M. Hu, V. V. Edara, V. I. Zarnitsyna, P. P. Aye, N. Golden, K. W. M. Green, B. M. Threeton, N. J. Maness, B. J. Beddingfield, R. P. Bohm, J. Dufour, K. Russell-Lodrigue, , B. Pulendran

This study shows that an adjuvanted subunit vaccine provides durable protection against SARS-CoV-2 Omicron in non-human primates, with strong neutralizing antibodies and memory T/B cells after booster doses.

bioRxiv · Mar 18, 2022 · PreprintImmunology

The pigtail macaque (Macaca nemestrina) model of COVID-19 reproduces diverse clinical outcomes and reveals new and complex signatures of disease

A. Melton, L. A. Doyle-Meyers, R. V. Blair, C. Midkiff, H. J. Melton, K. Russell-Lodrigue, P. P. Aye, F. Schiro, M. Fahlberg, D. Szeltner, S. Spencer, B. J. Beddingfield, K. Goff, N. Golden, T. Penney, , N. J. Maness

This study shows that pigtail macaques infected with SARS-CoV-2 exhibit mild-to-moderate disease with specific immune and viral dynamics, making them a potential model for studying COVID-19.

bioRxiv · Aug 28, 2021Immunology

An Orally Available Cathepsin L Inhibitor Protects Lungs Against SARS-CoV-2-Induced Diffuse Alveolar Damage in African Green Monkeys

F. W. Frueh, D. C. Maneval, R. P. Bohm, J. P. Dufour, R. V. Blair, S. Simpson, K. Powell, P. P. Aye, N. A. Golden, C. J. ROY, S. Spencer, K. Russell-Lodrigue, K. S. Plante, J. A. Plante, J. H. McKerrow, J. Rappaport

This study shows that the orally available cathepsin L inhibitor K777 reduces SARS-CoV-2-induced lung damage in African green monkeys.

bioRxiv · Jul 20, 2021 · PreprintImmunology

Cellular events of acute, resolving or progressive COVID-19 in SARS-CoV-2 infected non-human primates

M. D. Fahlberg, R. V. Blair, L. A. Doyle-Meyers, C. C. Midkiff, G. Zenere, K. E. Russell-Lodrigue, C. J. Monjure, E. H. Haupt, T. P. Penney, G. Lehmicke, B. M. Threeton, N. Golden, P. K. Datta, C. J. Roy, R. P. Bohm, , M. Vaccari

This study examines immune events in non-human primates infected with SARS-CoV-2, identifying cellular correlates of disease severity and potential therapeutic targets.

bioRxiv · Jul 21, 2020Immunology

Acute Respiratory Distress and Cytokine Storm in Aged, SARS-CoV-2 Infected African Green Monkeys, but not in Rhesus Macaques

R. V. Blair, M. Vaccari, L. A. Doyle-Meyers, C. J. Roy, K. Russell-Lodrigue, M. Fahlberg, C. J. Monjure, B. Beddingfield, K. S. Plante, J. A. Plante, S. C. Weaver, X. Qin, C. C. Midkiff, G. Lehmicke, N. Golden, , J. Rappaport

This study compares SARS-CoV-2 infection in aged African green monkeys and rhesus macaques, finding ARDS and cytokine storms in AGMs but not RMs.

bioRxiv · Jun 18, 2020 · PreprintPathology

Zika virus infection during pregnancy protects against secondary infection in the absence of CD8+ cells

B. Schouest, M. H. Gilbert, R. P. Bohm, F. Schiro, P. P. Aye, A. T. Panganiban, D. M. Magnani, N. J. Maness

This study shows that ZIKV infection during pregnancy provides protection against secondary infection without relying on CD8+ cells.

bioRxiv · May 8, 2020Immunology