Convergent alterations in the tumor microenvironment of MYC-driven human and murine prostate cancer
M. K. Graham, R. Wang, R. Chikarmane, B. Wodu, A. Vaghasia, A. Gupta, Q. Zheng, J. Hicks, P. Sysa-Shah, X. Pan, N. Castagna, J. Liu, J. Meyers, A. Skaist, Y. Zhang, , S. Yegnasubramanian
This study identifies MYC signaling activation as a common driver of tumor microenvironment alterations in human and murine prostate cancer through single-cell RNA-sequencing and comparative analysis.
bioRxiv · Sep 7, 2023Cancer Biology