Author

C. J. Bieberich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. M. De Marzo· 2 shared A. Gupta· 1 shared A. J. Korman· 1 shared A. M. Christiano· 1 shared A. Obradovic· 1 shared A. Skaist· 1 shared A. Vaghasia· 1 shared B. Simons· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

A. M. De Marzo

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2 papers

Recent·Most cited

Convergent alterations in the tumor microenvironment of MYC-driven human and murine prostate cancer

M. K. Graham, R. Wang, R. Chikarmane, B. Wodu, A. Vaghasia, A. Gupta, Q. Zheng, J. Hicks, P. Sysa-Shah, X. Pan, N. Castagna, J. Liu, J. Meyers, A. Skaist, Y. Zhang, , S. Yegnasubramanian

This study identifies MYC signaling activation as a common driver of tumor microenvironment alterations in human and murine prostate cancer through single-cell RNA-sequencing and comparative analysis.

bioRxiv · Sep 7, 2023Cancer Biology

Castration-mediated IL-8 Promotes Myeloid Infiltration and Prostate Cancer Progression

Z. A. Lopez-Bujanda, M. C. Haffner, M. G. Chaimowitz, N. Chowdhury, N. J. Venturini, A. Obradovic, C. S. Hansen, J. Jackow, K. S. Sfanos, C. J. Bieberich, P. J. Hurley, M. J. Selby, A. J. Korman, A. M. Christiano, A. M. De Marzo, C. G. Drake

This study identifies IL-8 secretion from prostate cancer cells during castration as a driver of myeloid infiltration and cancer progression, suggesting targeting IL-8/CXCR2 with immunotherapy could delay castration resistance.

bioRxiv · May 27, 2019Immunology