Author

B. T. Fife

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

M. K. Levings· 2 shared M. Mojibian· 2 shared V. Fung· 2 shared A. J. Dwyer· 1 shared C. B. Verchere· 1 shared C. M. Wardell· 1 shared C. Wardell· 1 shared E. Chen· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

M. K. Levings

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2 papers

Recent·Most cited

CAR Tregs mediate linked suppression and infectious tolerance in islet transplantation

C. Wardell, V. Fung, E. Chen, M. Haque, J. Gillies, J. Spanier, M. Mojibian, B. T. Fife, M. K. Levings

A2-CAR Tregs reduce BDC2.5 T cell engraftment, proliferation, and cytokine production, protecting mice from diabetes and inducing systemic tolerance.

bioRxiv · Apr 6, 2024 · PreprintImmunology

Insulin B peptide-MHC class II-specific chimeric antigen 1 receptor-Tregs prevent autoimmune diabetes

J. A. Spanier, V. Fung, C. M. Wardell, M. H. Alkhatib, Y. Chen, L. A. Swanson, A. J. Dwyer, M. E. Weno, N. Silva, J. S. Mitchell, P. C. Orban, M. Mojibian, C. B. Verchere, B. T. Fife, M. K. Levings

This paper demonstrates that InsB-g7 CAR Tregs specific for an insulin B-chain peptide prevent autoimmune diabetes in NOD mice.

bioRxiv · Feb 23, 2023 · PreprintImmunology