Author

C. M. Wardell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Approach:biophysical modeling· 1

Frequent Co-Authors

M. K. Levings· 2 shared M. Mojibian· 2 shared A. A. Ashkar· 1 shared A. J. Dwyer· 1 shared A. J. Lam· 1 shared A. Zhang· 1 shared B. T. Fife· 1 shared C. B. Verchere· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersImmunology

M. K. Levings

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Targeting the MR1-MAIT Cell Axis Improves Vaccine Efficacy and Affords Protection against Viral Pathogens

R. Rashu, M. Ninkov, C. M. Wardell, J. M. Benoit, N. I. Wang, M. R. D'Agostino, A. Zhang, E. Feng, N. Saeedian, G. I. Bell, F. Vahedi, D. A. Hess, R. M. Troyer, C. Y. Kang, A. A. Ashkar, , S. M. M. Haeryfar

This study shows that targeting the MR1-MAIT cell axis with 5-OP-RU enhances vaccine efficacy against viral pathogens by expanding and reprogramming MAIT cells.

PLOS Pathogens · Jun 29, 2023Peer-reviewedImmunology

Insulin B peptide-MHC class II-specific chimeric antigen 1 receptor-Tregs prevent autoimmune diabetes

J. A. Spanier, V. Fung, C. M. Wardell, M. H. Alkhatib, Y. Chen, L. A. Swanson, A. J. Dwyer, M. E. Weno, N. Silva, J. S. Mitchell, P. C. Orban, M. Mojibian, C. B. Verchere, B. T. Fife, M. K. Levings

This paper demonstrates that InsB-g7 CAR Tregs specific for an insulin B-chain peptide prevent autoimmune diabetes in NOD mice.

bioRxiv · Feb 23, 2023 · PreprintImmunology

PTEN is required for human Treg suppression of costimulation

A. J. Lam, M. Haque, K. A. Ward-Hartstonge, P. Uday, C. M. Wardell, J. K. Gillies, M. Speck, M. Mojibian, R. I. K. Geltink, M. K. Levings

This study shows PTEN is not essential for general Treg function but is required for their ability to suppress costimulatory molecule expression by antigen-presenting cells.

bioRxiv · Mar 6, 2022 · PreprintImmunology