J. Gillies

CAR Tregs mediate linked suppression and infectious tolerance in islet transplantation

A2-CAR Tregs reduce BDC2.5 T cell engraftment, proliferation, and cytokine production, protecting mice from diabetes and inducing systemic tolerance.

Functional effects of chimeric antigen receptor co-receptor signaling domains in human Tregs

This study compares ten CAR signaling domains in Tregs, finding that wild-type CD28 CARs are most effective in suppressing graft-versus-host disease.