Author

B. Yu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6 Bioengineering· 4 Immunology· 4 Biophysics· 3 Cancer Biology· 3 Cell Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 28 Research Focus:cell type annotation· 11 Research Focus:host-pathogen & immune response· 11 Organism:human· 11 Organism:mouse· 9 Assay:proteomics· 9 Research Focus:cell signaling & trafficking· 7 Research Focus:drug response / drug discovery· 6

Frequent Co-Authors

X. Li· 5 shared X. Wang· 5 shared Y. Liu· 4 shared B. Zhu· 3 shared F. Huang· 3 shared N. Neff· 3 shared R. Cheng· 3 shared X. Lu· 3 shared

Activity by Year

2018-2024 · peak 8/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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5 shared papersImmunology

X. Li

Mutual co-authors in cluster

Author profile →

34 papers

Recent·Most cited

Mapping of transgenic alleles in plants using a Nanopore-based sequencing strategy

S. Li, S. Jia, L. Hou, H. Nguyen, S. Sato, D. Holding, E. Cahoon, C. Zhang, T. Clemente, B. Yu

The paper introduces a Nanopore-based sequencing method to rapidly map transgenic alleles in the soybean genome, offering a high-throughput and cost-efficient approach.

bioRxiv · Jan 23, 2019Plant Biology

CRISPR/Cas9 gene editing for the creation of an MGAT1 deficient CHO cell line to control HIV-1 vaccine glycosylation

G. Byrne, S. M. O'Rourke, D. L. Alexander, B. Yu, R. Doran, M. Wright, Q. Chen, P. Azadi, P. W. Berman

This paper develops a CRISPR/Cas9-edited CHO cell line deficient in MGAT1 to produce HIV-1 gp120 with early glycosylation intermediates, enhancing binding to glycan-dependent broadly neutralizing antibodies.

bioRxiv · Jul 13, 2018Bioengineering

MITA couples with PI3K to regulate actin reorganization during BCR activation

C. Liu, Y. Jing, D. Kang, L. Yang, P. Jiang, N. Li, J. Cheng, J. Li, H. Miller, B. Ren, Q. Gong, W. Yin, Z. Liu, P. Mattila, B. Yu

This study shows MITA regulates BCR signaling through actin reorganization via the PI3K pathway, affecting B cell differentiation and autoimmune disease.

bioRxiv · Jun 15, 2018Immunology

Robotic selection for the rapid development of stable CHO cell lines for HIV vaccine for production

S. M. O'Rourke, G. Byrne, T. Gwen, W. Meredith, B. Yu, K. A. Mesa, R. C. Doran, D. Alexander, P. W. Berman

This paper develops a gene-edited CHO cell line and robotic selection method to improve Env expression and antigenic structure for HIV vaccine production.

bioRxiv · May 8, 2018Bioengineering