Author

P. Mattila

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 5

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 5 Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Assay:imaging· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

S. Hernandez-Perez· 4 shared A. V. Sarapulov· 2 shared E. Kuokkanen· 2 shared M. Vainio· 2 shared P. Petrov· 2 shared V. Sustar· 2 shared A. Bruckbauer· 1 shared A. F. Carisey· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersImmunology

S. Hernandez-Perez

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Proteomic profiling of isolated immune synapses from primary mouse B cells

D. M. Cunha, S. Hernandez-Perez, L. O. Awoniyi, A. F. Carisey, G. Jacquemet, P. Mattila

This study isolates and profiles immune synapses from primary mouse B cells to identify proteins involved in early activation by surface-bound antigens, revealing novel components and pathways.

bioRxiv · Feb 23, 2023 · PreprintImmunology

Loss of Rab8a in B cells leads to increased antibody responses and class-switch recombination

S. Hernandez-Perez, A. V. Sarapulov, M. O. Balci, E. Coffey, A. Harada, P. Mattila

This study shows that Rab8a deficiency in B cells increases antibody responses and class-switch recombination by altering signaling pathways.

bioRxiv · Sep 19, 2022 · PreprintImmunology

Missing-In-Metastasis / Metastasis Suppressor 1 modulates B cell receptor signaling, B cell metabolic potential and T cell-independent immune responses.

A. V. Sarapulov, P. Petrov, S. Hernandez-Perez, V. Sustar, E. Kuokkanen, R. Vinod, M. Vainio, L. Cords, M. Fritzsche, Y. Carrasco, P. Mattila

This study shows that MIM/MTSS1 regulates B cell receptor signaling, metabolic activity, and T cell-independent immune responses, with implications for cancer biology.

bioRxiv · Mar 8, 2020Immunology

B cells rapidly target antigen and surface-derived MHCII into peripheral degradative compartments.

S. Hernandez-Perez, M. Vainio, E. Kuokkanen, V. Sustar, P. Petrov, S. Forsten, V. Paavola, J. Rajala, L. Awoniyi, A. Sarapulov, H. Vihinen, E. Jokitalo, A. Bruckbauer, P. Mattila

This study identifies specialized early peripheral acidic vesicles (eMIIC) in B cells that facilitate rapid antigen processing and MHCII peptide loading for immune response.

bioRxiv · Oct 30, 2019Immunology

MITA couples with PI3K to regulate actin reorganization during BCR activation

C. Liu, Y. Jing, D. Kang, L. Yang, P. Jiang, N. Li, J. Cheng, J. Li, H. Miller, B. Ren, Q. Gong, W. Yin, Z. Liu, P. Mattila, B. Yu

This study shows MITA regulates BCR signaling through actin reorganization via the PI3K pathway, affecting B cell differentiation and autoimmune disease.

bioRxiv · Jun 15, 2018Immunology