Author

Benjamin Ciener

Columbia University Irving Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 4 Organism:human· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Research Focus:gene regulatory network inference· 3 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Andrew F. TeichiD· 4 shared Sandra LeskineniD· 3 shared Sharanya Sivakumar· 3 shared Annie OF HinikeriD· 2 shared Badri Narayan VardarajaniD· 2 shared Brittany N. DuggeriD· 2 shared Dennis W. DicksoniD· 2 shared Dolly Reyes‐DumeyeriD· 2 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersNeuroscience

Andrew F. TeichORCID

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Author profile →

4 papers

Recent·Most cited

Clonal CD8 T cells in the leptomeninges are locally controlled and influence microglia in human neurodegeneration

Ryan Hobson, Samuel H. S. Levy, Chitra Mohinder Singh Singal, Delaney Flaherty, Harrison Xiao, Benjamin Ciener, Hasini Reddy, Nick Zabinyakov, Christine Y. Kim, Andrew F. Teich, Neil A. Shneider, Elizabeth M. Bradshaw, Wassim Elyaman

The paper identifies clonal CD8 T cell activation in human meninges and their regulatory role in controlling neuroinflammation through interactions with natural killer cells.

Nature Immunology · Jan 27, 2026Peer-reviewedNeuroscience

An analysis of RNA quality metrics in human brain tissue

Jiahe Tian, Tiffany G. Lam, Sophie K. Ross, Benjamin Ciener, Sandra Leskinen, Sharanya Sivakumar, David A. Bennett, Vilas Menon, Guy M. McKhann, Alexi M. Runnels, Andrew F. Teich

The paper evaluates how pre-sequencing RNA quality metrics (PMI and RIN) correlate with post-sequencing RNA quality metrics and gene expression in human brain tissue.

Journal of Neuropathology & Experimental Neurology · Dec 9, 2024Peer-reviewedNeuroscience

MU-BRAIN: MUltiethnic Brain Rna-seq for Alzheimer INitiative

Zikun Yang, Basilio Cieza, Dolly Reyes‐Dumeyer, Annie Lee, Yiyi Ma, Elanur Yılmaz, Rafael Lantigua, Gary Wright Miller, Lewis M. Brown, Lawrence S. Honig, Benjamin Ciener, Sandra Leskinen, Sharanya Sivakumar, Badri Narayan Vardarajan, Brittany N. Dugger, , Giuseppe Tosto

The paper analyzes bulk RNA-seq data from diverse ethnic groups to identify differentially expressed genes and pathways in Alzheimer's Disease, highlighting cross-ethnic and ethnic-specific findings.

bioRxiv · Feb 20, 2024 · PreprintGenetics

Multi-omics Characterization of Epigenetic and Genetic Risk of Alzheimer Disease in Autopsied Brains from two Ethnic Groups

Yiyi Ma, Dolly Reyes‐Dumeyer, Angel L. Piriz, Patricia Recio, Diones Rivera Mejía, Martin A. Medrano, Rafael Lantigua, Jean Paul Vonsattel, Giuseppe Tosto, Andrew F. Teich, Benjamin Ciener, Sandra Leskinen, Sharanya Sivakumar, Michael A. Deture, Duara Ranjan, , Badri Narayan Vardarajan

The paper identifies six genetic loci associated with Alzheimer's disease in Hispanics, showing both genetic and epigenetic risks, with some downstream effects on mRNA expression being ethnicity-specific.

medRxiv · Feb 12, 2024 · PreprintGenetic & Genomic Medicine