Author

Harrison Xiao

Columbia University Irving Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Andrew F. TeichiD· 4 shared Anne Marie W. BartoschiD· 2 shared David Alan BennettiD· 2 shared Hasini Reddy· 2 shared Philip L. De JageriD· 2 shared Abby Vander LindeniD· 1 shared Adriana O. Mitchell· 1 shared Alexi M. RunnelsiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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4 shared papersNeuroscience

Andrew F. TeichORCID

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4 papers

Recent·Most cited

Clonal CD8 T cells in the leptomeninges are locally controlled and influence microglia in human neurodegeneration

Ryan Hobson, Samuel H. S. Levy, Chitra Mohinder Singh Singal, Delaney Flaherty, Harrison Xiao, Benjamin Ciener, Hasini Reddy, Nick Zabinyakov, Christine Y. Kim, Andrew F. Teich, Neil A. Shneider, Elizabeth M. Bradshaw, Wassim Elyaman

The paper identifies clonal CD8 T cell activation in human meninges and their regulatory role in controlling neuroinflammation through interactions with natural killer cells.

Nature Immunology · Jan 27, 2026Peer-reviewedNeuroscience

Bridging the Gap: Multi-Omics Profiling of Brain Tissue in Alzheimer's Disease and Older Controls in Multi-Ethnic Populations

Joseph S. Reddy, Laura M. Heath, Abby Vander Linden, Mariet Allen, Kátia de Paiva Lopes, Fatemeh Seifar, Erming Wang, Yiyi Ma, William L. Poehlman, Zachary Quicksall, Alexi M. Runnels, Yanling Wang, Duc M. Duong, Luming Yin, Kaiming Xu, , Nilüfer Ertekin‐Taner

This paper presents a multi-omics dataset from multi-ethnic Alzheimer's disease brain donors, including transcriptome, genome, and proteome data, to improve precision medicine for underrepresented populations.

Alzheimer s & Dementia · Aug 30, 2024Peer-reviewedNeuroscience

ZCCHC17 modulates neuronal RNA splicing and supports cognitive resilience in Alzheimer's disease

Anne Marie W. Bartosch, Elliot H. H. Youth, Shania Hansen, Yiyang Wu, Heather M. Buchanan, Maria E. Kaufman, Harrison Xiao, So Yeon Koo, Archana Ashok, Sharanya Sivakumar, Rajesh Kumar Soni, Logan C. Dumitrescu, Tiffany G. Lam, Ali S. Ropri, Annie Lee, , Andrew F. Teich

This study shows ZCCHC17 regulates RNA splicing in neurons and its dysfunction contributes to splicing abnormalities in Alzheimer's disease, with potential therapeutic implications.

Journal of Neuroscience · Nov 22, 2023Peer-reviewedNeuroscience

Neuroinflammation characterizes the earliest changes in Alzheimer's disease pathology and associated subjective cognitive impairment in adult hydrocephalus biopsies

Wenrui Huang, Anne Marie W. Bartosch, Harrison Xiao, Xena E. Flowers, Sandra Leskinen, Zeljko Tomljanovic, Gail M. Iodice, Deborah M. Boyett, Eleonora F. Spinazzi, Vilas Menon, Robert A. McGovern, Guy M. McKhann, Andrew F. Teich

The paper identifies gene expression changes in Alzheimer's disease pathology linked to cognitive impairment in hydrocephalus biopsies, showing microglial activation and loss of homeostatic genes.

bioRxiv · Oct 1, 2020 · PreprintNeuroscience