The regulation of Protein Phosphatase 4 by FBXO42 is required for cancer cell survival.
Stephan H. Spangenberg, Nicholas Garaffo, Enya Marie Catherine Alcindor, Benjamin L. Lusk, Vijaya Pandey, Adam D Longhurst, Emma Bolech, Becky Xu Hua Fu, Luke A. Gilbert, James Akira Wohlschlegel, David Paul Toczyski
This study identifies FBXO42's role in regulating PPP4C and p53 signaling, showing its importance in cancer cell survival through genetic and proteomic analyses.
EMBO Reports · Jul 14, 2026Peer-reviewedCell Biology