Author

Chesta Jain

University of MichiganORCID 0000-0003-3198-2820Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Costas Andreas LyssiotisiD· 2 shared Nicholas J. RossiteriD· 2 shared Peter SajjakulnukitiD· 2 shared Prarthana DalaliD· 2 shared Rashi SinghaliD· 2 shared Yatrik Madhukar ShahiD· 2 shared Boyan Hu· 1 shared Brandon CheniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Costas Andreas LyssiotisORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cancer BiologyCell MetabolismPeer-reviewedMay 27, 2026

Iron addicted colorectal cancers exploit Heme-Complex II axis to resist oxidative cell death

Chesta Jain, Muqit Essani, Roshan Kumar…·Yatrik Madhukar Shah

This study identifies a heme-SDH-CoQ axis that helps colorectal cancer cells resist iron-induced oxidative stress and cell death.

4 citationstop 1%

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologyCancer & MetabolismPeer-reviewedFeb 12, 2026

Targeting HIF-2α in Colorectal Cancer Reveals a Cholesterol Biosynthesis-Dependent Ferroptotic Vulnerability

Prarthana Dalal, Rashi Singhal, Boyan Hu…·Yatrik Madhukar Shah

This study identifies a metabolic vulnerability in colorectal cancer where combining HIF-2 inhibition with cholesterol biosynthesis inhibition using statins enhances ferroptosis, offering a new therapeutic strategy.

2 citationstop 5%

humanbulk RNA-seq

𝕏 PostBluesky