Author

Britta Fiedler

Osnabrück University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Joost C. M. HolthuisiD· 3 shared Milena WessingiD· 2 shared A. LehmanniD· 1 shared Angelika Hilderink· 1 shared Bianca M. EschiD· 1 shared Christian SchröeriD· 1 shared Elisabeth SüdhoffiD· 1 shared Emely Döffinger· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

Joost C. M. HolthuisORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

VPS13C/PARK23 initiates lipid transfer and membrane remodeling for efficient lysosomal repair

Oluwatobi Andrew Adeosun, Christian Schröer, Elisabeth Südhoff, Fabio Bergenthal, Katharina Sommer, Emely Döffinger, Britta Fiedler, Angelika Hilderink, A. Lehmann, Lea-Sophie Pohle, Sergei M. Korneev, Florian Fröhlich, Kenji Maeda, Rainer Kurre, Michael Holtmannspötter, , Joost C. M. Holthuis

This study identifies VPS13C/PARK23 as a key protein involved in lysosomal repair by facilitating lipid transfer and membrane remodeling in response to damage.

Nature Communications · Jul 2, 2026Peer-reviewedCell Biology

Challenging a role for ceramide channels and microdomains in apoptosis induction using a bottom-up approach

Milena Wessing, Sophie Klaßen, Britta Fiedler, Katia Cosentino, Joost C. M. Holthuis

This study challenges models of ceramide-induced apoptosis by showing ceramides cannot form channels or substitute for cardiolipin in Bax pore formation.

bioRxiv · Nov 14, 2025 · PreprintBiochemistry

Key determinants of VDAC-hexokinase I complex assembly revealed by a minimal vesicle-based interaction assay

Milena Wessing, Isabelle Watrinet, Michael Timme, Britta Fiedler, Manuel N. Melo, Jacob Piehler, Joost C. M. Holthuis

The paper develops an in vitro assay to study HKI-VDAC1 complex assembly and shows the critical role of a bilayer-facing glutamate in pH-sensitive binding.

bioRxiv · Nov 3, 2025 · PreprintBiophysics