Author

Isabelle Watrinet

Osnabrück University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:microscopy & imaging analysis· 1 Approach:statistical model· 1

Frequent Co-Authors

Jacob PiehleriD· 2 shared Britta Fiedler· 1 shared Changjiang YouiD· 1 shared Jinye LiiD· 1 shared Joost C. M. HolthuisiD· 1 shared Julia Dohle· 1 shared K. Christopher GarcíaiD· 1 shared Manuel N. MeloiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

Jacob PiehlerORCID

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2 papers

Recent·Most cited

Long-term single molecule localization microscopy uncovers dynamic co-assembly of Lrp6 and Ror2 into Wnt-signalosomes

Michael Philippi, Julia Dohle, Isabelle Watrinet, Michael Holtmannspötter, Jinye Li, Oliver Birkholz, Yi Miao, Ulrich Rothbauer, K. Christopher García, Rainer Kurre, Jacob Piehler, Changjiang You

This study uses single-molecule tracking to show that Lrp6 and Ror2 co-assemble into hybrid Wnt signalosomes dynamically.

Science Signaling · Mar 3, 2026Peer-reviewedBiophysics

Key determinants of VDAC-hexokinase I complex assembly revealed by a minimal vesicle-based interaction assay

Milena Wessing, Isabelle Watrinet, Michael Timme, Britta Fiedler, Manuel N. Melo, Jacob Piehler, Joost C. M. Holthuis

The paper develops an in vitro assay to study HKI-VDAC1 complex assembly and shows the critical role of a bilayer-facing glutamate in pH-sensitive binding.

bioRxiv · Nov 3, 2025 · PreprintBiophysics