Author

Marie‐Laure Yaspo

Max Planck Institute for Molecular GeneticsORCID 0000-0002-9555-9979Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Frances BurdeniD· 2 shared Hendrik G. StunnenbergiD· 2 shared Joost H.A. MartensiD· 2 shared Kate DownesiD· 2 shared Laura ClarkeiD· 2 shared Mattia FrontiniiD· 2 shared Myrto A. KostadimaiD· 2 shared Paul FlicekiD· 2 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Frances BurdenORCID

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3 papers

Recent·Most cited

Lineage-restricted dependency on an oncofetal SNHG29-IGF2BP1 RNA axis in acute megakaryoblastic leukemia

Robert E. Winkler, Bruno Griesler, Wolfgang Sippl, Reinier Abraham Boon, Stefanie Dimmeler, Ilka Wittig, Marie‐Laure Yaspo, Stefan Hüttelmaier, Raj Bhayadia, Dirk Heckl, Jan‐Henning Klusmann

This study identifies SNHG29 and IGF2BP1 as a lineage-specific oncogenic circuit in AMKL, showing their dependency and therapeutic vulnerability.

Leukemia · Jun 30, 2026Peer-reviewedCancer Biology

Cell type specific novel lincRNAs and circRNAs in the BLUEPRINT haematopoietic transcriptomes atlas.

Luigi Grassi, Osagie G. Izuogu, Natasha Andressa Nogueira Jorge, Denis Seyres, Mariona Bustamante, Frances Burden, Samantha Farrow, Neda Farahi, Fergal J. Martin, Adam Frankish, Jonathan M. Mudge, Myrto A. Kostadima, Romina Petersen, John J. Lambourne, Sophia Rowlston, , Mattia Frontini

The paper identifies novel long non-coding RNAs and circular RNAs in hematopoietic cells using BLUEPRINT consortium data, highlighting their cell type specificity.

bioRxiv · Sep 10, 2019 · PreprintGenomics

Comparative analysis of neutrophil and monocyte epigenomes

Daniel Rico, Joost H.A. Martens, Kate Downes, Enrique Carrillo de Santa Pau, Véra Pancaldi, Alessandra Breschi, David Richardson, Simon Charles Heath, Sadia Saeed, Mattia Frontini, Lu Chen, Stephen B. Watt, Fabian Müller, Laura Clarke, Hindrik H. D. Kerstens, , Hendrik G. Stunnenberg

This study compares the epigenomes of neutrophils and monocytes to identify regulatory elements and chromatin states, revealing differences in enhancer activity and DNA methylation.

bioRxiv · Dec 22, 2017 · PreprintGenomics