Utilizing an acute hyperthermia-induced seizure test and pharmacokinetic studies to establish optimal dosing regimens in a mouse model of Dravet syndrome
J. A. Mensah, K. Johnson, T. Freeman, C. A. Reilly, J. E. Rower, C. S. Metcalf, K. S. Wilcox
This study evaluates combination therapies for Dravet Syndrome using a mouse model, finding that triple-drug regimens enhance seizure control through potential drug interactions.
bioRxiv · Oct 3, 2023Pharmacology & Toxicology