Author

C. Coyne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

C. Bakkenist· 2 shared A. Evans· 1 shared A. I. Wells· 1 shared A. Saied· 1 shared A. Wells· 1 shared C. Kenway· 1 shared C. Midkiff· 1 shared C. Perdios· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersMicrobiology

C. Bakkenist

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Immune Correlates of Hyperglycemia and Vaccination in a Non-human Primate Model of Long-COVID

C. S. Palmer, C. Perdios, M. Abdel-Mohsen, J. Mudd, P. Datta, N. Maness, G. Lehmicke, N. Golden, L. Hellmer, C. Coyne, K. Moore Green, C. Midkiff, K. Williams, R. Tiburcio, M. Fahlberg, , J. Rappaport

This study establishes a non-human primate model of metabolic PASC, identifies immune correlates of hyperglycemia, and shows vaccine-induced glycemic improvement.

bioRxiv · Sep 22, 2023 · PreprintImmunology

Trophoblast organoids with physiological polarity model placental structure and function

L. Yang, P. Liang, H. Yang, C. Coyne

The paper develops trophoblast organoids with physiological polarity to model placental structure and function, showing improved hormone secretion and syncytium size.

bioRxiv · Jan 12, 2023Cell Biology

Respiratory and intestinal epithelial cells exhibit differential susceptibility and innate immune responses to contemporary EV-D68 isolates

M. C. Freeman, A. I. Wells, J. Anstadt, M. M. Myerburg, J. Ciomperlik-Patton, C. Coyne

The paper compares the susceptibility and innate immune responses of respiratory and intestinal epithelial cells to different EV-D68 isolates, finding differential type III IFN responses.

bioRxiv · Jan 5, 2021Microbiology

Human FcRn expression and Type I Interferon signaling control Echovirus 11 pathogenesis in mice

A. Wells, K. Grimes, K. Kim, E. Branche, C. Bakkenist, W. DePas, S. Shresta, C. Coyne

This study shows that hFcRn and IFN signaling determine echovirus pathogenesis in mice, with hFcRn-IFNAR-/- mice modeling human disease.

bioRxiv · Sep 24, 2020Microbiology

The neonatal Fc receptor is a pan-echovirus receptor

S. Morosky, A. Evans, K. Lemon, S. Schmus, C. Bakkenist, C. Coyne

This study identifies the neonatal Fc receptor (FcRn) as a receptor for all echoviruses, explaining increased neonatal susceptibility to these viruses.

bioRxiv · Oct 9, 2018Microbiology