Prostaglandin E2 induction by cytosolic Listeria monocytogenes in phagocytes is necessary for optimal T-cell priming
C. E. McDougal, Z. T. Morrow, S. Kim, D. Carter, D. M. Stevenson, D. Amador-Noguez, M. J. Miller, J.-D. Sauer
This study identifies PGE2 production via COX-2 as a cytosol-dependent innate immune response critical for CD8+ T-cell priming against L. monocytogenes.
bioRxiv · Mar 23, 2021 · PreprintImmunology