Author

E. C. Britt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:metabolism & bioenergetics· 2 Assay:metabolomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

J. Fan· 3 shared A. Huttenlocher· 2 shared A. J. Walsh· 1 shared A. Wagner· 1 shared C. D. Fletcher· 1 shared C. E. McDougal· 1 shared H. Khan· 1 shared J. A. Votava· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersBiochemistry

J. Fan

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Author profile →

3 papers

Recent·Most cited

Activation-induced shift in nutrient preference and function-specific nutrient dependence in human neutrophils

E. C. Britt, X. Qing, J. A. Votava, J. Lika, A. Wagner, S. Shen, N. L. Arp, H. Khan, S. M. Schieke, C. D. Fletcher, A. Huttenlocher, J. Fan

This study shows that human neutrophils shift nutrient preference from glycogen to glucose upon activation, with function-specific metabolic dependencies.

bioRxiv · Sep 25, 2023Biochemistry

Reversed upper glycolysis and rapid activation of oxidative pentose phosphate pathway supports the oxidative burst in neutrophils

E. C. Britt, J. Fan

This paper shows that neutrophils use reversed upper glycolysis and rapid oxidative pentose phosphate pathway activation to support the oxidative burst, a key immune response.

bioRxiv · Nov 25, 2020 · PreprintBiochemistry

In vivo fluorescence lifetime imaging captures metabolic changes in macrophages during wound responses in zebrafish

V. Miskolci, K. Tweed, M. Lasarev, E. C. Britt, C. E. McDougal, A. J. Walsh, J. Fan, J.-D. Sauer, M. Skala, A. Huttenlocher

This paper uses in vivo FLIM to track metabolic changes in macrophages during wound responses in zebrafish, showing dynamic shifts in NAD(P)H and FAD redox ratios.

bioRxiv · Jun 16, 2020Immunology