Author

C. Hoebartner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Siewert· 1 shared C. Dienemann· 1 shared C. Ghosh· 1 shared C. Kisker· 1 shared D. Tegunov· 1 shared E. Greiter· 1 shared F. Sauer· 1 shared F. Seitz· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperBiochemistry

A. Siewert

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Trapped in translocation: Stalling of XPD on a crosslinked DNA substrate

J. Kuper, T. Hove, S. Maidl, F. Sauer, M. Kempf, E. Greiter, H. Neitz, C. Hoebartner, C. Kisker

This study uses cryo-EM to reveal how XPD helicase stalls on interstrand crosslinked DNA, identifies functional residues, and suggests a model for NER bubble formation.

bioRxiv · Feb 20, 2024 · PreprintBiochemistry

A side-by-side comparison of peptide-delivered antisense antibiotics employing different nucleotide mimics

C. Ghosh, L. Popella, V. Dhamodharan, J. Jung, L. Barquist, C. Hoebartner, J. Vogel

This study compares seven chemically distinct antisense oligomers targeting Salmonella acpP, finding only PNA and PMO are effectively delivered by a KFF peptide to inhibit bacterial growth.

bioRxiv · Jul 11, 2023Microbiology

Mechanism of SARS-CoV-2 polymerase inhibition by remdesivir

G. Kokic, H. S. Hillen, D. Tegunov, C. Dienemann, F. Seitz, J. Schmitzova, L. Farnung, A. Siewert, C. Hoebartner, P. Cramer

This study elucidates how remdesivir inhibits SARS-CoV-2 RNA-dependent RNA polymerase by causing RNA synthesis stalling through a translocation barrier.

bioRxiv · Oct 28, 2020Biochemistry