Chitinase 3-like-1 Contributes to Acetaminophen-induced Liver Injury by Promoting Hepatic Platelet Recruitment
Z. Shan, L. Li, C. L. Atkins, M. Wang, Y. Wen, J. Jeong, N. Moreno, D. Feng, X. Gui, N. Zhang, C. G. Lee, J. A. Elias, W. Lee, B. Gao, F. W. Lam, , C. Ju
This study identifies Chi3l1 as a key mediator of acetaminophen-induced liver injury by promoting hepatic platelet recruitment through the CD44 axis.
bioRxiv · Apr 8, 2021Pharmacology & Toxicology