Author

C. Kobayashi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:multiome· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

J. Jung· 2 shared Y. Sugita· 2 shared A. Mateus· 1 shared A. Typas· 1 shared B. Pfalz· 1 shared C. Sureau· 1 shared C. Tan· 1 shared D. Ugarte La Torre· 1 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersBiophysics

J. Jung

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Implementation of residue-level coarse-grained models in GENESIS for large-scale molecular dynamics simulations

C. Tan, J. Jung, C. Kobayashi, D. Ugarte La Torre, S. Takada, Y. Sugita

The paper implements residue-level coarse-grained models in GENESIS to enable large-scale molecular dynamics simulations of biomolecules, improving computational efficiency and handling heterogeneous systems.

bioRxiv · Oct 21, 2021Biophysics

The Inherent Flexibility of Receptor Binding Domains in SARS-CoV-2 Spike Protein

H. M. Dokainish, S. Re, T. Mori, C. Kobayashi, J. Jung, Y. Sugita

This study identifies multiple conformational states of the SARS-CoV-2 Spike protein's receptor binding domain through molecular dynamics simulations, highlighting structural flexibility important for drug and vaccine design.

bioRxiv · Aug 6, 2021Biophysics

Identification of anti-severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) oxysterol derivatives in vitro

H. Ohashi, F. Wang, F. Stappenbeck, K. Tsuchimoto, C. Kobayashi, W. Saso, M. Kataoka, K. Kuramochi, M. Muramatsu, T. Suzuki, C. Sureau, M. Takeda, T. Wakita, F. Parhami, K. Watashi

This study identifies oxysterol derivatives with anti-SARS-CoV-2 activity, showing that Oxy210 and Oxy232 inhibit viral replication by disrupting double membrane vesicles.

bioRxiv · Jan 31, 2021Microbiology

Bacterial retrons encode tripartite toxin/antitoxin systems

J. Bobonis, A. Mateus, B. Pfalz, S. Garcia-Santamarina, M. Galardini, C. Kobayashi, F. Stein, M. M. Savitski, J. R. Elfenbein, H. Andrews-Poymenis, A. Typas

The paper identifies retrons as a novel family of tripartite toxin/antitoxin systems in bacteria, with the reverse transcriptase and msDNA functioning as antitoxin components.

bioRxiv · Jun 22, 2020Microbiology