Author

S. Re

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:mechanistic / dynamical model· 3 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Assay:structural biology· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Y. Sugita· 3 shared A. Nishimura· 1 shared A. Satsuka· 1 shared A. Shinobu· 1 shared C. Kobayashi· 1 shared D. Tomokiyo· 1 shared H. Asakura· 1 shared H. M. Dokainish· 1 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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3 shared papersBiophysics

Y. Sugita

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The impact of inhibitor size and flexibility on the binding pathways to c-Src kinase

A. Shinobu, S. Re, Y. Sugita

This study uses molecular dynamics simulations to show that inhibitor size and flexibility affect binding pathways and energetics to c-Src kinase, influencing residence time.

bioRxiv · Oct 25, 2022Biophysics

The Inherent Flexibility of Receptor Binding Domains in SARS-CoV-2 Spike Protein

H. M. Dokainish, S. Re, T. Mori, C. Kobayashi, J. Jung, Y. Sugita

This study identifies multiple conformational states of the SARS-CoV-2 Spike protein's receptor binding domain through molecular dynamics simulations, highlighting structural flexibility important for drug and vaccine design.

bioRxiv · Aug 6, 2021Biophysics

Clomipramine suppresses ACE2-mediated SARS-CoV-2 entry

Y. Kato, S. Yamada, K. Nishiyama, A. Satsuka, S. Re, D. Tomokiyo, J. M. Lee, T. Tanaka, A. Nishimura, K. Yonemitsu, H. Asakura, Y. Ibuki, Y. Imai, N. Kamiya, K. Mizuguchi, , M. Nishida

This study shows clomipramine inhibits SARS-CoV-2 entry into cardiomyocytes and synergizes with remdesivir to suppress infection.

bioRxiv · Mar 13, 2021 · PreprintPharmacology & Toxicology

Molecular basis for two stereoselective Diels-Alderases that produce decalin skeletons

K. Fujiyama, N. Kato, S. Re, K. Kinugasa, K. Watanabe, R. Takita, T. Nogawa, T. Hino, H. Osada, Y. Sugita, S. Takahashi, S. Nagano

This study determines the molecular mechanisms of two Diels-Alderases that produce enantiomeric decalin scaffolds through structural and computational analyses.

bioRxiv · Feb 1, 2021Biochemistry