Author

C. L. Healy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Physiology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

G. C. Shearer· 3 shared B. M. Wagner· 2 shared D. J. Gyberg· 2 shared K. A. Murphy· 2 shared T. D. O'Connell· 2 shared B. A. Harsch· 1 shared B. C. Jensen· 1 shared B. Harsch· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersPhysiology

G. C. Shearer

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Free fatty acid receptor 4 in cardiac myocytes ameliorates ischemic cardiomyopathy

M. J. Zhang, S. Karachenets, D. J. Gyberg, S. Puccini, C. L. Healy, S. C. Wu, G. C. Shearer, T. D. O'Connell

This study shows that Ffar4 in cardiac myocytes reduces systolic dysfunction after ischemia-reperfusion by improving mitochondrial function and cGMP signaling.

bioRxiv · Apr 12, 2024Physiology

Free fatty acid receptor 4 (FFAR4) regulates cardiac oxylipin balance to promote inflammation resolution in a model of heart failure preserved ejection fraction secondary to metabolic syndrome

N. Zhang, K. A. Murphy, B. Harsch, M. Zhang, D. J. Gyberg, B. M. Wagner, J. Mendelson, M. T. Patterson, D. A. Orchard, C. L. Healy, J. W. Williams, G. C. Shearer, T. O'Connell

This study shows that Ffar4 loss worsens cardiac inflammation and remodeling in male HFpEF-MetS mice by altering oxylipin balance.

bioRxiv · Apr 13, 2022 · PreprintPhysiology

Free fatty acid receptor 4 is a nutrient sensor that resolves inflammation to maintain cardiac homeostasis

K. A. Murphy, B. A. Harsch, C. L. Healy, S. S. Joshi, S. Huang, R. E. Walker, B. M. Wagner, K. M. Ernste, W. Huang, R. Block, C. D. Wright, N. Tintle, B. C. Jensen, G. C. Shearer, T. D. O'Connell

This study shows Ffar4 resolves inflammation in the heart by sensing fatty acids and promoting anti-inflammatory oxylipin production, preventing cardiac remodeling.

bioRxiv · Sep 25, 2019 · PreprintPhysiology