C. Lehmann

The grass that built the Central Highland of Madagascar: environmental niches and morphological diversity of Loudetia simplex

This study examines the environmental and morphological variation of Loudetia simplex in Madagascar and Africa, finding that Malagasy populations represent a single species with distribution patterns linked to environmental factors.

Circulating neutrophils from patients with early breast cancer have distinct subtype-dependent phenotypes

This study identifies subtype-specific phenotypic and signaling changes in circulating neutrophils from early breast cancer patients compared to healthy volunteers.

The unique ORF8 protein from SARS-CoV-2 binds to human dendritic cells and induces a hyper-inflammatory cytokine storm

This study shows that SARS-CoV-2's ORF8 protein binds to human dendritic cells, induces cytokine storms, and may be a target for therapeutic intervention.

The Aspartyl Protease Ddi1 Is Essential for Erythrocyte Invasion by the Malaria Parasite

This study shows that PfDdi1 proteolytic activity is essential for Plasmodium falciparum erythrocyte invasion and identifies it as a potential antimalarial target.

T cells expressing multiple co-inhibitory molecules in acute malaria are not exhausted but exert a suppressive function

The paper identifies malaria-induced T cells expressing co-inhibitory molecules that are not exhausted but have suppressive function, resembling regulatory T cells.

Kinetics and correlates of the neutralizing antibody response to SARS-CoV-2

This study examines the kinetics and correlates of the SARS-CoV-2 neutralizing antibody response in 963 recovered individuals over 10 months, finding variations in antibody persistence and identifying factors predicting neutralizing activity.

Lineage Functional Types (LFTs): Characterizing functional diversity to enhance the representation of ecological behavior in Earth System Models

The paper develops lineage-based functional types (LFTs) to improve Earth System Models by incorporating phylogenetic relatedness and trait variation in grasses.

Functional diversification enabled grassy biomes to fill global climate space

The paper maps global grassy biomes and identifies key traits and lineages driving their distribution across climates.

Characterization of P. falciparum dipeptidyl aminopeptidase 3 specificity reveals structural factors responsible for differences in amino acid preferences between peptide-based substrates and covalent inhibitors.

The paper characterizes P. falciparum DPAP3 specificity and identifies structural factors causing differences in amino acid preferences between peptide substrates and covalent inhibitors.

Plasmodium falciparum dipeptidyl aminopeptidase 3 activity is important for efficient erythrocyte invasion by the malaria parasite

This study shows that DPAP3 protease activity is crucial for Plasmodium falciparum erythrocyte invasion but not egress.