Author

M. Poreba

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Organism:chicken / avian· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

M. Drag· 3 shared K. Groborz· 2 shared A. Asman· 1 shared A. Biela· 1 shared A. Dauphinee· 1 shared B. Turk· 1 shared C. Lehmann· 1 shared D. Kowalczyk· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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3 shared papersBiochemistry

M. Drag

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Glycosaminoglycans act as activators of peptidylarginine deiminase 4

G. P. Bereta, E. Bielecka, K. Marzec, L. Pijanowski, A. Biela, P. Wilk, M. Kaminska, J. Nowak, E. Wator, P. Grudnik, D. Kowalczyk, J. Koziel, P. Mydel, M. Poreba, T. Kantyka

This study identifies glycosaminoglycans as activators of PAD4, showing they enhance Ca2+ affinity and induce NETosis, with implications for rheumatoid arthritis.

bioRxiv · Jun 17, 2024 · PreprintBiochemistry

Thermoprotection by a cell membrane-localized metacaspase in a green alga

Y. Zou, I. Sabljic, N. Horbach, A. Dauphinee, A. Asman, L. S. Temino, M. Drag, S. Stael, M. Poreba, J. Stahlberg, P. Bozhkov

This study identifies CrMCA-II, a metacaspase in Chlamydomonas reinhardtii, which provides thermoprotection through modulating plasma membrane fluidity, independent of its proteolytic activity.

The Plant Cell · Nov 16, 2023Peer-reviewedPlant Biology

The Activome: multiplexed probing of activity of proteolytic enzymes using mass cytometry-compatible activity-based probes (TOF-probes)

M. Poreba, K. Groborz, W. Rut, M. Pore, S. J. Snipas, M. Vizovisek, B. Turk, M. Drag, G. S. Salvesen

The paper develops lanthanide-labeled activity-based probes for mass cytometry to multiplex protease activity detection, demonstrating their use in identifying protease activomes in cell lines and blood cells.

bioRxiv · Sep 23, 2019Biochemistry

Characterization of P. falciparum dipeptidyl aminopeptidase 3 specificity reveals structural factors responsible for differences in amino acid preferences between peptide-based substrates and covalent inhibitors.

L. E. de Vries, M. I. Sanchez, K. Groborz, L. Kuppens, M. Poreba, C. Lehmann, F. Yuan, S. Arastu-Kapur, M. Horn, M. Mares, M. Bogyo, M. Drag, E. Deu

The paper characterizes P. falciparum DPAP3 specificity and identifies structural factors causing differences in amino acid preferences between peptide substrates and covalent inhibitors.

bioRxiv · Aug 10, 2018 · PreprintBiochemistry