MicrobiologybioRxiv
Disrupting the plastid-hosted iron-sulfur cluster biogenesis pathway in Toxoplasma gondii has pleiotropic effects irreversibly impacting parasite viability
E. A. Renaud, S. Pamukcu, A. Cerutti…·S. Besteiro
This study shows that disrupting the SUF iron-sulfur cluster pathway in Toxoplasma gondii severely impairs parasite growth and viability through multiple metabolic and functional defects.
DOI 10.1016/j.jbc.2022.102243