Author
J. M. Johnson
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2019-2023 · peak 4/yrCo-Author Collaboration Network
10 top collaborators · 43 mutual co-author links8 papers
Recent·Most cited
Weight loss improves skeletal muscle mitochondrial energy efficiency
P. J. Ferrara, M. J. Lang, J. M. Johnson, S. Watanabe, K. L. McLaughlin, J. A. Maschek, A. R. Verkerke, P. Siripoksup, A. Chaix, J. E. Cox, K. H. Fisher-Wellman, K. Funai
This study shows weight loss increases skeletal muscle mitochondrial energy efficiency by altering cardiolipin composition, which reduces energy expenditure and prevents weight regain.
bioRxiv · Dec 21, 2022 · PreprintPhysiology
Mitochondrial Phosphatidylethanolamine Directly Regulates UCP1 to Promote Brown Adipose Thermogenesis
J. M. Johnson, A. D. Peterlin, E. Balderas, E. G. Sustarsic, J. A. Maschek, M. J. Lang, A. Jara-Ramos, V. Panic, J. T. Morgan, C. J. Villanueva, A. Sanchez, J. Rutter, I. J. Lodhi, J. E. Cox, K. H. Fisher-Wellman, , K. Funai
This study shows mitochondrial phosphatidylethanolamine directly regulates UCP1 to control thermogenesis in brown adipose tissue.
bioRxiv · Aug 26, 2022 · PreprintBiochemistry
Lipid hydroperoxides promote sarcopenia through carbonyl stress
H. Eshima, J. L. Shahtout, P. Siripoksup, M. J. Pearson, Z. S. Mahmassani, P. J. Ferrara, A. W. Lyons, J. A. Maschek, A. D. Peterlin, A. R. P. Verkerke, J. M. Johnson, A. Salcedo, J. J. Petrocelli, E. R. Miranda, E. J. Anderson, , K. Funai
This study shows lipid hydroperoxides contribute to sarcopenia by causing carbonyl stress, and their neutralization prevents muscle atrophy and weakness.
bioRxiv · Dec 17, 2021Physiology
The Lands cycle modulates plasma membrane lipid organization and insulin sensitivity in skeletal muscle
P. J. Ferrara, X. Rong, J. A. Maschek, A. R. Verkerke, P. Siripoksup, H. Song, K. C. Krishnan, J. M. Johnson, J. Turk, J. A. Houmard, A. J. Lusis, J. E. Cox, S. R. Shaikh, P. Tontonoz, K. Funai
The study identifies LPCAT3 as a key regulator of plasma membrane lipid organization and insulin sensitivity in skeletal muscle, showing its role in modulating lipid metabolism and insulin action.
bioRxiv · Dec 23, 2019 · PreprintPhysiology
Gradual decrease in the inter-population diversity of HIV-1 Env among group M lineages worldwide
C. Han, J. M. Johnson, R. Dong, R. Kandula, A. J. Kort, M. Wong, T. Yang, P. J. Breheny, G. D. Brown, H. Haim
The paper analyzes the evolution of HIV-1 Env diversity across clades and regions, finding that inter-population diversity decreases while intra-population diversity increases due to conserved selective pressures.
bioRxiv · Sep 4, 2019 · PreprintEvolutionary Biology
Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity
T. D. Heden, J. M. Johnson, P. J. Ferrara, H. Eshima, A. R. Verkerke, E. J. Wentzler, P. Siripoksup, T. M. Narowski, C. B. Coleman, C.-T. Lin, T. E. Ryan, P. T. Reidy, L. E. de Castro Bras, C. M. Karner, C. F. Burant, , K. Funai
The paper shows that mitochondrial phospholipids, specifically phosphatidylethanolamine (PE), regulate respiratory capacity in skeletal muscle, with PE deficiency causing respiratory failure and oxidative stress.
bioRxiv · Apr 9, 2019Physiology
Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening
O. W. Lee, S. M. Austin, M. R. Gamma, D. M. Cheff, T. D. Lee, K. M. Wilson, J. M. Johnson, J. C. Travers, J. C. Braisted, R. Guha, C. Klumpp-Thomas, M. Shen, M. D. Hall
The paper profiles cytotoxicity of over 100,000 compounds across normal and cancer cell lines to identify cytotoxic compounds and improve screening efficiency.
bioRxiv · Feb 5, 2019Cell Biology