Pptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis
N. M. Niemi, G. M. Wilson, K. A. Overmyer, F.- N. Vogtle, D. C. Lohman, K. L. Schueler, A. D. Attie, C. Meisinger, J. J. Coon, D. J. Pagliarini
This study shows that Pptc7 is essential for mitochondrial metabolism and biogenesis, as its deletion in mice causes metabolic defects and early death.
bioRxiv · Sep 25, 2018Biochemistry