Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
8 papers
Recent·Most cited
F. Kraus, Y. He, S. Swarup, K. A. Overmyer, J. Brenner, C. Capitanio, A. Bieber, A. Jen, N. M. Nightingale, B. J. Anderson, C. Lee, J. A. Paulo, I. R. Smith, J. M. Plitzko, S. P. Gygi, , J. W. Harper
This study uses nMOST to profile proteo-lipidomics in lysosomal storage disease mutants, revealing autophagy defects and mitochondrial dysfunction.
bioRxiv · Mar 26, 2024Cell Biology
C. Mathai, F. L. Jourd'heuil, L. G. C. Pham, K. Gilliard, J. Balnis, A. Jen, K. A. Overmyer, J. J. Coon, A. Jaitovich, B. Boivin, D. Jourd'heuil
This study shows cytoglobin regulates intracellular hydrogen peroxide and redox signals by reducing hyperoxidation of peroxiredoxins and facilitating Hyper7 reduction, independent of heme-based hydrogen peroxide reactions.
bioRxiv · Mar 31, 2023 · PreprintBiochemistry
J. Tai, R. M. Guerra, S. W. Rogers, Z. Fang, L. K. Muehlbauer, E. Shishkova, K. A. Overmyer, J. J. Coon, D. J. Pagliarini
The paper identifies Hem25p as a mitochondrial IPP transporter in yeast, essential for CoQ biosynthesis.
bioRxiv · Mar 14, 2023 · PreprintBiochemistry
M. Manicki, H. Aydin, L. A. Abriata, K. A. Overmyer, R. M. Guerra, J. J. Coon, M. Dal Peraro, A. S. Frost, D. J. Pagliarini
The paper presents the structure and functional analysis of a multimeric COQ7:COQ9 complex involved in CoQ biosynthesis, revealing its mechanism for accessing hydrophobic precursors and coordinating CoQ synthesis.
Molecular Cell · Nov 1, 2022Peer-reviewedBiochemistry
L. F. Schimke, A. H. Marques, G. C. Baiocchi, C. A. Prado, D. L. Fonseca, P. P. Freire, D. R. Placa, I. S. Filgueira, R. C. Salgado, G. Jansen-Marques, A. E. Oliveira, J. P. S. Peron, G. Cabral Miranda, J. A. M. Barbuto, N. O. S. Camara, , O. C. Marques
This study identifies a shared neutrophil activation signature between severe COVID-19 and other acute inflammatory conditions, suggesting common therapeutic targets.
bioRxiv · Jul 30, 2021Immunology
I. J. Miller, S. R. Peters, K. A. Overmyer, B. R. Paulson, M. S. Westphall, J. J. Coon
This paper explores using urine metabolomics to monitor health in real time through a smartphone app and discusses initial findings from two healthy subjects.
bioRxiv · Jun 24, 2019Biochemistry
N. M. Niemi, G. M. Wilson, K. A. Overmyer, F.- N. Vogtle, D. C. Lohman, K. L. Schueler, A. D. Attie, C. Meisinger, J. J. Coon, D. J. Pagliarini
This study shows that Pptc7 is essential for mitochondrial metabolism and biogenesis, as its deletion in mice causes metabolic defects and early death.
bioRxiv · Sep 25, 2018Biochemistry
I. M. Velsko, K. A. Overmyer, C. Speller, M. Collins, L. Loe, L. A. F. Frantz, J. B. Rodriguez Martinez, E. Chavez, L. Klaus, K. Sankaranarayanan, C. M. Lewis, J. J. Coon, G. Larson, C. Warinner
This study characterizes the metabolome of modern and historic dental calculus to identify patterns of metabolite persistence and loss over time.
bioRxiv · May 9, 2017Microbiology