Systemic LSD1 inhibition prevents aberrant remodeling of metabolism in obesity
B. Ramms, D. P. Pollow, H. Zhu, C. Nora, A. R. Harrington, I. Omar, P. Gordts, M. Wortham, M. Sander
This study shows that systemic LSD1 inhibition reduces obesity-related metabolic issues like NAFLD and improves insulin sensitivity in mice without affecting lean mice.
bioRxiv · Nov 25, 2021Physiology