P. Davies

Assessment of the efficacy of field and laboratory methods for the detection of Tropilaelaps spp.

The paper compares field and laboratory methods for detecting Tropilaelaps mites, finding that novel methods are more effective than existing ones.

One for all - Human kidney Caki-1 cells are highly susceptible to infection with corona- and other respiratory viruses

This paper identifies Caki-1 human kidney cells as a highly susceptible model for studying multiple respiratory viruses, including coronaviruses and influenza, offering a versatile platform for cross-virus comparison.

Elaboration of a MALDI-TOF Mass Spectrometry-based Assay of Parkin Activity and High-Throughput screening platform for Parkin Activators

The paper develops two MALDI-TOF MS-based methods to quantify Parkin E3 ligase activity in vitro, enabling high-throughput screening of Parkin activators.

S-acylation stabilizes ligand-induced receptor kinase complex formation during plant pattern-triggered immune signalling.

This study shows S-acylation stabilizes activated receptor kinase complexes at the plasma membrane, enhancing immune signaling in plants.

Characterization of protease activity of Nsp3 from SARS-CoV-2 and its in vitro inhibition by nanobodies

This study characterizes Nsp3 protease activity from SARS-CoV-2 and identifies nanobodies that inhibit PLpro with nanomolar affinity.

Structural basis of ligand selectivity by a bacterial adhesin lectin involved in multi- species biofilm formation

The paper determines the structural basis of ligand selectivity in MpPA14, a bacterial adhesin lectin, showing it binds specific monosaccharides and polysaccharides through distinct interactions.

Molecular basis for inhibition of adhesin-mediated bacterial-host interactions through a novel peptide-binding domain

The paper identifies a peptide-binding domain in a bacterial adhesion protein and develops ligands that inhibit its function, suggesting potential for disrupting harmful bacterial-host interactions.

Macro-to-nano scale investigation of wall-plate joints in the acorn barnacle Semibalanus balanoides: correlative imaging, biological form and function, and bioinspiration

The paper uses correlative imaging techniques to analyze the microstructural and crystallographic properties of barnacle wall-plate joints, revealing functionally-graded orientations and nano-scale pore networks.

Taking a deeper look: Quantifying the differences in fish assemblages between shallow and mesophotic temperate rocky reefs

This study compares fish assemblages between shallow and mesophotic temperate reefs, finding significant differences driven by specific species and depth-related ecological factors.

Phylostratigraphic analysis of tumor and developmental transcriptomes reveals relationship between oncogenesis, phylogenesis and ontogenesis

The paper analyzes the evolutionary ages of cancer-related genes and finds they are enriched for pre-Metazoan genes, suggesting cancer reverts to an ancestral state.