Author

Carmen Da Silva

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Adam Samuel SperlingiD· 1 shared Andrew E. H. EliaiD· 1 shared Cameron Schluter· 1 shared Cyrus Jin· 1 shared Deumaya ShresthaiD· 1 shared Edward WangiD· 1 shared Eric S. FischeriD· 1 shared Eugene OhiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCell Biology

Adam Samuel SperlingORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Distinct Proteasomal Pathways Drive Oncogenic PPM1D Activation

Ni Yan, Deumaya Shrestha, Cameron Schluter, Cyrus Jin, Edward Wang, Carmen Da Silva, Ilaria Gritti, Nikolaos Tsopoulidis, Ruxin Yang, Adam Samuel Sperling, Jonathan M. Tsai, Andrew E. H. Elia, Eric S. Fischer, Mikolaj Michal Slabicki, Eugene Oh, Peter Grant Miller

This study shows that truncating mutations in PPM1D shift its degradation pathway from ubiquitin-independent to UBR5-mediated, leading to increased PPM1D levels and oncogenic effects.

bioRxiv · Jun 9, 2026 · PreprintCell Biology