Author

Chengyan Zhao

University of Pennsylvania

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Organism:rat· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Andrew Jesse ConnelliD· 3 shared Ashwin N. SkellyiD· 3 shared Barton F. HaynesiD· 3 shared Beatrice H. HahniD· 3 shared Bette KorberiD· 3 shared George M. ShawiD· 3 shared Hui LiiD· 3 shared John W. CareyiD· 3 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Andrew Jesse ConnellORCID

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Author profile →

3 papers

Recent·Most cited

Shared Maturation Pathways of HIV-1 Envelope-reactive V3-glycan bnAb Lineages in Human and Rhesus Macaque

Matthew Clark, Hui Li, Mitchell Martin, Tyler D. Evangelous, S. Gobeil, Madison Berry, Kshitij Wagh, Elena E. Giorgi, Michael P. Hogarty, Chengyan Zhao, Shuyi Wang, Lorie Marchitto, Wenge Ding, Younghoon Park, Juliette M. Rando, , Wilton B. Williams

The paper identifies shared maturation pathways of V3-glycan broadly neutralizing antibody lineages in humans and rhesus macaques, revealing convergent mutations and evolution patterns.

bioRxiv · Jan 30, 2026 · PreprintImmunology

Consistent Induction of Broadly Neutralizing HIV Antibodies by a Novel Two-Step Mechanism Informs Immunogen Design

Ashwin N. Skelly, Harry B. Gristick, Hui Li, Edem Gavor, Andrew J. Connell, Edward F. Kreider, Lorie Marchitto, Michael P. Hogarty, Maddy L. Newby, Joel D. Allen, Weimin Liu, Anthony P. West, Kasirajan Ayyanathan, Mary S. Campion, Kaitlyn Winters, , George M. Shaw

This study shows a novel two-step mechanism for inducing broadly neutralizing HIV antibodies in macaques using a modified SHIV, informing vaccine design.

bioRxiv · Oct 6, 2025 · PreprintImmunology

Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV-1 V2 apex broadly neutralizing antibody development

Rumi Habib, Ryan S. Roark, Hui Li, Andrew Jesse Connell, Michael P. Hogarty, Kshitij Wagh, Shuyi Wang, Lorie Marchitto, Ashwin N. Skelly, John W. Carey, Kirsten J. Sowers, Kasirajan Ayyanathan, Samantha J. Plante, Frédéric Bibollet‐Ruche, Young-Hoon Park, , George M. Shaw

The paper identifies B cell priming as the main obstacle to developing HIV-1 V2 apex broadly neutralizing antibodies in SHIV-infected macaques.

bioRxiv · May 3, 2025 · PreprintImmunology