The Rossmann2x2 Fold Attains its Native Structure Via a Defined Pathway of Sequential and Cooperative Folding Units
Robert P. Sosa, JeongHoon Kim, Alex Tong, Sudeesh Krishnamurthy, Christina Volz, Bendix Heβ, Daniel Pineda, Carlos Bustamante
This study uses single-molecule force spectroscopy to show that the Rossmann2x2 fold protein folds via a defined pathway of sequential and cooperative folding units.
bioRxiv · Sep 18, 2026 · PreprintBiophysics