Pannexin 1 Ablation Disrupts Cell Cycle Progression and Compromises the Structure of Melanoma Tumours
Stephanie E. Leighton, Danielle E. Johnston, Kevin Barr, Brooke L. O’Donnell, Wyatt J. Schug, Matthew S. Huver, Dan Stefan, Christopher A. Bonham, John Joseph Kelly, Ying Xia, Brant E. Isakson, John Andrew Ronald, Dale W. Laird, Silvia Peñuela
This study shows that PANX1 ablation disrupts cell cycle progression and tumor structure in melanoma, suggesting it as a therapeutic target.
bioRxiv · Oct 9, 2026 · PreprintCancer Biology