A chromosome region linked to neurodevelopmental disorders acts in distinct neuronal circuits in males and females to control locomotor behavior
Jaekyoon Kim, Yann S. Vanrobaeys, M. Felicia Davatolhagh, Benjamin A. Kelvington, Snehajyoti Chatterjee, Sarah L. Ferri, Christopher C. Angelakos, Alea A. Mills, Marc Vincent Fuccillo, Thomas Nickl‐Jockschat, Ted G. Abel
This study identifies sex- and cell type-specific transcriptomic and behavioral effects of 16p11.2 hemideletion in mice, revealing distinct impacts on striatal circuits and locomotor behavior.
bioRxiv · May 17, 2024 · PreprintNeuroscience