Class III PI3K is essential for Wingless secretion and Evi/Wls recycling in Drosophila
Michaela Holzem, Bojana Pavlović, Mareike Munz, Claudia Strein, Jan Gerwin, Marko Lampe, Fillip Port, Michael Boutros
The paper identifies Vps15 as essential for endocytosis-dependent Wg secretion and reveals divergent post-endocytic fates of Wg and Evi/Wls in Drosophila.
bioRxiv · May 20, 2025 · PreprintDevelopmental Biology