Reflection confocal microscopy for quantitative assessment of airway surface liquid dysregulation and pharmacological rescue in cystic fibrosis under near-physiological conditions
Ayça Seyhan Agircan, Marko Lampe, Heike Scheuermann, Tobias Albrecht, Simon Y. Graeber, Anita Balázs, Ingo Baumann, Stephan Block, Rainer Pepperkok, Marcus Alexander Mall, Julia Duerr
This paper introduces confocal reflection microscopy as a method to measure airway surface liquid height in cystic fibrosis models without perturbing the ASL, showing it is sensitive to detect ASL changes and therapeutic responses.
Scientific Reports · Dec 11, 2025Peer-reviewedCell Biology