Author

Corriene E. Sept

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Genetic & Genomic Medicine· 2 Genomics· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 4 Approach:statistical model· 3 Assay:ChIP-seq· 2 Approach:experimental assay· 2 Research Focus:fine-mapping· 2 Research Focus:gene regulatory network inference· 2 Research Focus:GWAS / association mapping· 2 Assay:GWAS summary statistics· 2

Frequent Co-Authors

Alex P. ReineriD· 2 shared Anders S. HanseniD· 2 shared Andrew D. JohnsoniD· 2 shared Anne BolandiD· 2 shared Bruce M. PsatyiD· 2 shared Charles L KooperbergiD· 2 shared Christian G. Cerda-SmithiD· 2 shared Christine Elissa EyleriD· 2 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenetic & Genomic Medicine

Alex P. ReinerORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Multi-ancestry polygenic risk scores for venous thromboembolism

Yon Ho Jee, Florian Thibord, Alicia Dominguez, Corriene E. Sept, Kristin M. Boulier, Vidhya Venkateswaran, Yi Ding, Tess Cherlin, Shefali S. Verma, Valeria Lo Faro, Traci M. Bartz, Anne Boland, Jennifer A. Brody, Jean‐François Deleuze, Joseph Emmerich, , Peter Kraft

This study develops multi-ancestry polygenic risk scores for venous thromboembolism using diverse GWAS data and shows improved predictive performance across European- and African-ancestry populations.

Human Molecular Genetics · Jun 3, 2024Peer-reviewedGenetic & Genomic Medicine

High-resolution CTCF footprinting reveals impact of chromatin state on cohesin extrusion dynamics

Corriene E. Sept, Y. Esther Tak, Christian G. Cerda-Smith, Haley M. Hutchinson, Viraat Y. Goel, Marco Blanchette, Mital S. Bhakta, Anders S. Hansen, J. Keith Joung, Sarah E. Johnstone, Christine Elissa Eyler, Martin J. Aryee

The paper uses high-resolution CTCF MNase HiChIP data to analyze chromatin loop structures and introduces FactorFinder, finding that fully extruded CTCF-CTCF loops are rare and that chromatin state affects cohesin extrusion dynamics.

bioRxiv · Oct 20, 2023 · PreprintGenomics

Integrative PTEN Enhancer Discovery Reveals a New Model of Enhancer Organization

Christian G. Cerda-Smith, Haley M. Hutchinson, Annie Liu, Viraat Y. Goel, Corriene E. Sept, Holly Kim, Salvador Casaní-Galdón, Katherine G. Burkman, Christopher F. Bassil, Anders S. Hansen, Martin J. Aryee, Sarah E. Johnstone, Christine Elissa Eyler, Kris C. Wood

The paper identifies 10 PTEN enhancers and proposes a new model of enhancer organization that includes spatial separation of functional and structural elements.

bioRxiv · Sep 20, 2023 · PreprintGenomics

Cross-Ancestry Investigation of Venous Thromboembolism Genomic Predictors

Florian Thibord, Derek M. Klarin, Jennifer A. Brody, Ming‐Huei Chen, Michael G. Levin, Daniel I. Chasman, Ellen L. Goode, Kristian Hveem, Maris Teder‐Laving, Ángel Martínez-Pérez, Dylan Aïssi, Delphine Daian-Bacq, Kaoru Ito, Pradeep Natarajan, Pamela L. Lutsey, , Nicholas L. Smith

This study identifies 135 genomic loci associated with venous thromboembolism risk through cross-ancestry GWAS and provides insights into biological pathways and potential therapeutic targets.

Circulation · Oct 17, 2022Peer-reviewedGenetic & Genomic Medicine