Author

Haley M. Hutchinson

Duke UniversityORCID 0000-0002-8181-6022Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genomics· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Assay:ChIP-seq· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Christian G. Cerda-SmithiD· 3 shared Anders S. HanseniD· 2 shared Christine Elissa EyleriD· 2 shared Corriene E. Sept· 2 shared Kris C. WoodiD· 2 shared Martin J. AryeeiD· 2 shared Sarah E. JohnstoneiD· 2 shared Viraat Y. GoeliD· 2 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersGenomics

Christian G. Cerda-SmithORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BRCA1-A and LIG4 complexes mediate ecDNA biogenesis and cancer drug resistance

Oliver W. Chung, Shun Yao, Ling Wang, Fu Yang, Lauren Schier, Melissa Aldana, Christian G. Cerda-Smith, Haley M. Hutchinson, Kris C. Wood, Weijia Su, Mustafa Khasraw, Lee Zou, Dale A. Ramsden, ZZ Zhao Zhang

This study identifies BRCA1-A and LIG4 complexes as mediators of ecDNA biogenesis and shows their role in cancer drug resistance.

Proceedings of the National Academy of Sciences · Mar 11, 2026Peer-reviewedCancer Biology

High-resolution CTCF footprinting reveals impact of chromatin state on cohesin extrusion dynamics

Corriene E. Sept, Y. Esther Tak, Christian G. Cerda-Smith, Haley M. Hutchinson, Viraat Y. Goel, Marco Blanchette, Mital S. Bhakta, Anders S. Hansen, J. Keith Joung, Sarah E. Johnstone, Christine Elissa Eyler, Martin J. Aryee

The paper uses high-resolution CTCF MNase HiChIP data to analyze chromatin loop structures and introduces FactorFinder, finding that fully extruded CTCF-CTCF loops are rare and that chromatin state affects cohesin extrusion dynamics.

bioRxiv · Oct 20, 2023 · PreprintGenomics

Integrative PTEN Enhancer Discovery Reveals a New Model of Enhancer Organization

Christian G. Cerda-Smith, Haley M. Hutchinson, Annie Liu, Viraat Y. Goel, Corriene E. Sept, Holly Kim, Salvador Casaní-Galdón, Katherine G. Burkman, Christopher F. Bassil, Anders S. Hansen, Martin J. Aryee, Sarah E. Johnstone, Christine Elissa Eyler, Kris C. Wood

The paper identifies 10 PTEN enhancers and proposes a new model of enhancer organization that includes spatial separation of functional and structural elements.

bioRxiv · Sep 20, 2023 · PreprintGenomics