Author

D. A. Hanna

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:metabolism & bioenergetics· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

C. A. Lyssiotis· 2 shared C. M. Moore· 2 shared R. Banerjee· 2 shared A. Andren· 1 shared A. D. Patterson· 1 shared A. Guha· 1 shared A. Parolia· 1 shared A. R. Reddi· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCell Biology

C. A. Lyssiotis

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Author profile →

4 papers

Recent·Most cited

BRD4-mediated epigenetic regulation of endoplasmic reticulum-mitochondria contact sites is governed by the mitochondrial complex III

B. Chen, D. C. Stark, P. V. Jadhav, T. M. Lynn-Nguyen, B. S. Halligan, N. J. Rossiter, N. Sindoni, M. Shin, J. A. Paulo, M. Chang, I. Koo, S. Koshkin, S. Eyunni, P. Ronchi, M. T. Paulsen, , Y. M. Shah

The paper identifies fedratinib as a drug that increases endoplasmic reticulum-mitochondria contact sites by inhibiting BRD4, revealing a novel epigenetic pathway linking ERMCS to cellular metabolism.

bioRxiv · Feb 2, 2024 · PreprintCell Biology

H2S preconditioning induces long-lived perturbations in O2 metabolism

D. A. Hanna, J. Diessl, A. Guha, R. A. Kumar, A. Andren, C. A. Lyssiotis, R. Banerjee

This study shows that H2S preconditioning causes long-lasting changes in O2 metabolism, including increased P50(O2) and metabolic memory effects lasting up to 24-48 hours.

bioRxiv · Oct 20, 2023 · PreprintBiochemistry

Depletion Assisted Hemin Affinity (DAsHA) Proteomics Reveals an Expanded Landscape of Heme Binding Proteins

H. Kim, C. M. Moore, S. Mestre-Fos, D. A. Hanna, L. D. Williams, A. Reddi, M. P. Torres

The paper introduces a chemoproteomics method to identify heme-binding proteins, revealing new roles for heme in chromatin remodeling, DNA repair, RNA splicing, and vesicular trafficking.

bioRxiv · Oct 11, 2022 · PreprintBiochemistry

Heme oxygenase-2 (HO-2) binds and buffers labile heme, which is largely oxidized, in human embryonic kidney cells

D. A. Hanna, C. M. Moore, L. Liu, X. Yuan, A. S. Fleischhacker, I. Hamza, S. W. Ragsdale, A. R. Reddi

This study shows HO-2 binds and buffers oxidized labile heme in HEK293 cells, regulating heme homeostasis by controlling bioavailability rather than degrading heme under non-stress conditions.

bioRxiv · Jun 6, 2021Cell Biology