Author

D. De Nardo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

E. Latz· 2 shared A. Mansell· 1 shared C. Bradfield· 1 shared C. Louis· 1 shared D. Garama· 1 shared D. Gough· 1 shared F. Humphries· 1 shared F. Kirby· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersImmunology

E. Latz

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2 papers

Recent·Most cited

STAT3 Serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1β expression

J. Balic, H. Albargy, K. Luu, F. Kirby, W. Jayasekara, F. Mansell, D. Garama, N. Baschuk, D. De Nardo, C. Louis, F. Humphries, K. A. Fitzgerald, E. Latz, D. Gough, A. Mansell

This study shows that STAT3 Ser727 phosphorylation is essential for TLR4-induced metabolic reprogramming and IL-1β production in inflammation.

Nature Communications · Jul 30, 2020Peer-reviewedImmunology

IRAK1-mediated coincidence detection of microbial signals licenses inflammasome activation

S. J. Vayttaden, M. Smelkinson, O. Ernst, R. J. Carlson, J. Sun, C. Bradfield, M. G. Dorrington, J. Liang, N. Bouladoux, R. A. Gottschalk, K.-S. Oh, G. Pegoraro, S. Ganesan, D. De Nardo, E. Latz, , I. D. C. Fraser

This study identifies IRAK1-mediated supramolecular organizing centers that coordinate multiple immune pathways to license inflammasome activation in response to microbial signals.

bioRxiv · Dec 26, 2019 · PreprintImmunology